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The purpose of using optical coherence tomography (OCT) to detect refractory amblyopia thickness of the retina of the eye , to explore refractory amblyopia whether the morphological changes of the retina exists to provide a theoretical basis for its pathogenesis . Ophthalmology , the Affiliated Hospital of Qingdao University Medical College April May 2010 -2011 outpatient amblyopia the refractory amblyopic eyes of 27 patients with 30 as the experimental group , elect non - refractory amblyopia 22 cases 30 , the diopter lt ; ± 1.00D of the same age normal children 19 cases of 30 as a control group . Optical coherence tomography (Opti cal Coherence Tomography OCT) of the macular area of the experimental group and a control group of children with a quick scan , measuring the fovea , the central area (1mm diameter range ) and next to the central area ( diameter of 3 mm annular area within ) above the average retinal thickness , below , the nasal and temporal side to compare different regions of retinal thickness difference . Results the refractory amblyopic eye , non- refractory amblyopia , normal control eye foveal thickness were 198.83 ± 32.33μm , ??from 189.57 ± 29.59μm and 178.10 ± 29.29μm, group differences were statistically significant (P = for 0.03,0.004 lt; 0.001 ( P lt; 0.05 ) refractory amblyopic eye , non - refractory amblyopia normal control eye macular the average thickness of the central area of ??225.47 ± 19.85μm from 219.93 ± 18.55μm and 213.47 ± 28.33μm, three groups , P values ??were P = 0.03,0.045 , lt; 0.001 , the differences were statistically significant ( P lt; 0.05 ) above the central area next to the macula , the bottom , the nasal and temporal side of the retina The thickness of the refractory amblyopic eye 298.70 ± 27.71μm , 298.63 ± 26.36μm , 298.00 ± 31.5 μm , 292.27 ± 30.04μm , and non - refractory amblyopia were 300.10 ± 25.46μm . 297.33 ± 31.04μm , 298.33 ± 34.23μm , 286.57 ± 24.87μm, normal control eyes were as 297.07 ± 23.28μm 294.57 ± 39.27μm 299.07 ± 24.48μm 294.57 ± 39.27μm four quadrants retinal thickness between the three groups , the differences were not statistically significant sense ( P gt; 0.05). conclusion refractory amblyopic eye fovea , the central area of retinal thickness increases above the central area next to the macula , below the nasal and temporal retinal thickness did not change significantly .
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