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This paper uses pressure microwave-assisted , orthogonal pressurized microwave-assisted and response surface methodology pressurized microwave-assisted extraction of total flavonoids EHD research process . The results show that the three processes of the optimal conditions were as follows: microwave power 700w, irradiation time 50s (3 times ) , 50% aqueous ethanol concentration , the ratio of 1:10 ; microwave power 700w, pressure 131.733kPa, aqueous ethanol concentration of 50 % , the ratio of 1:10 ; microwave power 700w, aqueous ethanol concentration of 51.2% , leaching pressure 131.733kPa, liquid to solid ratio of 10.45 . Three kinds of optimum conditions to obtain the total flavonoids were 70.46% , 97.28% and 98.75% . Response surface methodology and Design-Expert software processing the experimental data , the extraction rate of total flavonoids obtained ternary quadratic mathematical model : Y = -484.09 13.46X 1 6.07X 2 < / sub> 4.30X 3 2.33 × 10 -3 sup> X 1 X 2 0.015X 1 < / sub> X 3 -2.94 × 10 -4 sup> X 2 X 3 -0.70X 1 2 sup>-0.023X 2 2 sup>-0.043X 3 2 sup> by experimental validation , the model and the experimental values ??are very consistent and predictable under different conditions of total flavonoids extraction rate . Design and manufacture of Teflon pressurized microwave-assisted extraction device has a simple structure , convenient operation, saving energy and significantly improve the extraction rate of total flavonoids , etc., suitable for laboratory use, and amplification for industrial production .
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