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A Clinical and Experimental Study of Mobilization and Immobilization Effects on Ankle Joint Function of Postoperative Achilles Tendon Rupture
Author: DaReBai·ReDaTi
Tutor: BaiJingPing
School: Xinjiang Medical University
Course: Surgery
Keywords: Achilles tendon rupture Immobilization Anchylosis Synovial fluid Protein chip
CLC: R687.2
Type: Master's thesis
Year: 2009
Downloads: 27
Quote: 0
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Abstract
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Objective: To investigate the clinical Achilles tendon rupture postoperative brake on ankle function and limb braking rabbit ankle joint fluid differential protein expression . Method : follow-up , in line with the Achilles tendon completely rupture diagnostic criteria , 35 patients were randomly divided into 17 cases of exercise therapy group and braking group, 18 patients , and follow - up of two groups of patients with ankle Cedell objective and subjective ankle function evaluation criteria . 16 select healthy New Zealand white rabbits were randomly divided into brake 8 the exercise group 8 , two groups of rabbits underwent unilateral tenotomy after umbrella suture suture limb long leg cast brake group was given a fixed , exercise group not brake , after 21 days extract two sets of limb ankle fluid , obtained specimens application of SELDI-TOF-MS technology to analyze the differences in the expression of the protein spectrum of different model of the ankle joint solution . Results: (1) Cedell evaluation criteria , sports were excellent in 14 cases (81.3 %) , good in 3 cases (18.7%) , excellent rate of 100% . Braking were excellent in 10 cases , good in 5 cases , and poor in 3 cases , good rate of 83% . ( 2 ) 27 M / Z peak exercise group and braking mass spectrometry data after the initial screening , the relative strength to do Wilconxon rank sum test analysis 9 P values ??less than 0.05 M / Z peak from the significantly different protein peaks any combination thereof , ( 2 ) M / Z markers located 1235,1508 Da , higher expression in the brake group , and low expression in the exercise groups . Conclusion reduce Achilles tendon rupture : a certain degree of exercise therapy on postoperative immobilization on ankle function . Brake group of high expression of the protein peak ankle liquid to produce a specific protein , it may cause a series of pathological and physiological changes , which affect the function of the brake ankle .
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CLC: > Medicine, health > Surgery > Orthopaedic Surgery ( movement system diseases,orthopedic surgery ) > Orthopedic surgery and surgery > Muscle and tendon surgery
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