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Objective: of subacute eczema is eczema stage, most studies, subacute eczema symptoms of transition is acute eczema and chronic eczema. Currently, eczema in dermatology is more common in autumn and winter predilection, accounting for 10% -15% of the total number of patients of outpatient, but also lower the cure rate of a class of diseases. TCM treatment according to the patient's clinical manifestations meticulous syndrome type, depending on the disease type, use a different prescription targeted therapy, patients with clinical symptoms improved significantly, especially with a low recurrence rate, and adverse reactions. Although the long-term efficacy of TCM treatment is obvious, but the recent markedly slow, is not conducive to enhance the confidence of patients attending and compliance; modern medical research more eczema allergic diseases classified as antihistamines and corticosteroids drugs, according to the cause focus Oral and topical symptomatic treatment, short-term effect, but the cure rate is low, and the recurrence rate was high. The pros and cons of Chinese and Western medicine treatment alone, the combination of a variety of literature and ancient old TCM research the essence of the subject, according to Zhang Zhili addition and subtraction of the old man's prescription, since the proposed the spleen dampness party joint resistance by drug imidazole Sting sustained release tablets in the treatment of subacute eczema, systematic observation of its clinical efficacy in the treatment of Spleen wet Yun disease type subacute eczema patients and explore its mechanism, aimed at finding a new Integrative Medicine methods to increase the cure rate and reduce the recurrence probability. Methods: 100 patients met the inclusion criteria were randomly divided into combined treatment group and the control group, the observation of 50 cases. Combined treatment group given the spleen dampness party (set of square: barley Cork Atractylodes fried lentils Citrus aurantium capillaris Sophora flavescens Ait skullcap, Dictamni,,, Alisma Cynanchum method: a daily, Jianshui 500ml, 2 times orally) and mizolastine sustained-release tablets (10mg, once a day, half an hour before bedtime oral); mizolastine control group were given oral sustained-release tablets. Both groups were continuous medication for 28 days to assess the efficacy, partially recovered patients healed after the January and March, follow-up, observing two groups before and after treatment the skin lesions total score change, itching as well as relapse rate and the comparison of the adverse reactions. Results: the spleen dampness combined Mizolastine sustained-release tablets and with mizolastine sustained-release tablets can ease the patient's symptoms, treatment 28 days after the total efficiency of 96% and 84%, respectively, cure rate and healed month follow-up, follow-up results in March on statistical calculations are p <0.05, significant difference in the cure rate and recurrence rate of the combined treatment group than the control group. Tracking adverse reactions, the combined treatment group patients with cases of stomach discomfort, 2% of the incidence of adverse reactions of the two groups of patients. Control group patients had seven cases of lethargy, one cases of dry mouth, 14% of the one cases of fatigue, two cases of stomach burning sensation, nausea, dizziness, 3 cases of headache, the incidence of adverse reactions, the statistics show, p <0.05, different The combination of adverse reaction rates lower than the control group. conclusion: the spleen dampness combined Mizolastine sustained-release tablets and with mizolastine sustained-release tablets sustained-release tablets can improve the spleen wet Yun permit subacute eczema patients the clinical symptoms, symptom scores before and after treatment were decreased, but the spleen dampness combined Mizolastine sustained-release tablets Spleen wet Yun permit the improvement of clinical symptoms than with mizolastine sustained-release tablets in the treatment and mizolastine side effects is less than with sustained-release tablets were cured January, March follow-up, the recurrence rate of the combined group is much lower than that of the control group, so the combination is better than a single medication.
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