Dissertation > Excellent graduate degree dissertation topics show

Common TCM syndrome and serum homocysteine ??and diastolic function relationships of the newly diagnosed patients with type 2 diabetes

Author: BaiSong
Tutor: GaoTianShu
School: Liaoning University of Traditional Chinese Medicine
Course: Traditional Chinese Medicine
Keywords: diabetes disturbance of the spleen due to damp-heat subclinical hypothyroidism blood lipid homocysteine diastolic function
CLC: R259
Type: Master's thesis
Year: 2011
Downloads: 3
Quote: 0
Read: Download Dissertation


Objective:Study on the change of the blood lipid, homocysteine and diastolic function when the diabetes combined with subclinical hypothyroidism of common Traditional Chinese Medicine syndrome type, to understand the relationship between the subclinical hypothyroidism and the atherosclerosis. The effect of subclinical hypothyroidism on the diastolic function also investigated. This study would provide theoretical basis for intervention treatment of the patients with disturbance of the spleen due to damp-heat diabetes combined with subclinical hypothyroidism.Method:Collected in Endocrine Department of Shenzhou hospital inpatient or outpatient endocrinology diabetes in patients with disturbance of the spleen due to damp-heat diabetes combined with subclinical hypothyroidism(DSDH group) and diabetes but with normal thyroid function (Impairment of both QI and YIN, IBQY group) cases for each 20 cases. At the same time, 20 persons were selected from community residents without diabetes and normal thyroid function as a control group. The thyroid function (FT3, FT4, TSH), fasting plasma glucose (FPG), glycosylated hemoglobin (HbA1c), serum triglyceride (TG), total Cholesterol (TC), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), serum homocysteine (Hcy) and cardiac ultrasonography were tested. Test results were statistical analysized and established the relationship between the indicators and interaction mechanisms.Results:1.Serum TSH level of DSDH group were significantly higher than the control group and IBQY group (P<0.05), there was significant difference. There was no significant difference of the FT3 and FT4 (P>0.05). FPG and HbA1c levels of DSDH group and IBQY group were significantly higher than the control group (P<0.05), but there was no significant difference between DSDH group and IBQY group (P>0.05).2.Plasma total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), serum triglyceride (TG) of DSDH group and IBQY group were higher than the control group, but high-density lipoprotein cholesterol (HDL-C) was lower (P<0.05), there was significant difference. And the TC、TG、LDL-C level was no significant difference between two groups (P>0.05) although the levels of DSDH group were a little higher. Serum homocysteine (Hcy) of DSDH group was higher than the IBQY group and control group, there was significant difference (P<0.05). And the Hcy level of IBQY group was a little higher than the control group, but two groups was no significant difference (P>0.05).3.Em, Am and Em / Am values of DSDH group and IBQY group were significant lower than the control group (P<0.05). And Em, Am and Em / Am values of DSDH group were reduced slightly compared with IBQY group, but there was no significant difference (P>0.05).Conclusions:1.Remarkable dyslipidemia and diastolic dysfunction are accompanied with impairment of both QI and YIN and disturbance of the spleen due to damp-heat.2.Homocysteine level of DSDH group is significantly increased suggestting that this type of patients more susceptible to atherosclerosis. Intervention treatment should be carried out at early stage.

Related Dissertations

  1. Cloning and Expression Analysis of GPx, GST and SAHH Genes in Chlamydomonas Sp. ICE-L from Antarctica,Q943.2
  2. Serum A-FABP Levels and Its Expression in Atherosclerotic Plaques of Diabetes Mellitus,R587.1
  3. C-reactive protein,homocysteine ??levels in type 2 diabetic peripheral neuropathy of TCM,R259
  4. The Supercritical Carbon Dioxide Extraction and Functional Quality Evaluation of Camellia Seed Oil,TS225.16
  5. Professor Liu Yanchi academic thought and clinical experience and clinical studies for treatment of diabetes,R249
  6. The Effect and Pharmacological Analysis of Houttuynia Cordata Thunb (HCT) on Diabetes Mellitus,R285.5
  7. Effect of High Glucose on Chemokine Ligand 16 (CXCL16) Expression and Secretion in THP-1 Macrophages and Intervention of Aspirin in the Activity,R587.2
  8. The Relationship of Polymorphisms of Methionine Synthase Reductase(MTRR) Gene and Plasma Homocysteine Levels with Myocardial Infarction,R542.22
  9. The Effect and Mechanism of p38MAPK Inhibitor CBS3830 on Intimal Hyperplasia in Autogenous Vein Grafts of Diabetic Rats,R587.1
  10. Effect of β-Casomorphin7 or Casein Peptides on Blood Glucose and Oxidative Stress of the Diabetic Rats,R587.1
  11. Experimental Study of Influence of Atrovastatin on Expression of NF-κB in Retionpathy of Diabetic Rats,R587.1
  12. Relationship between Level of Serum Uric Acid and Lower Extremity Arterial Disease in Patients with Type 2 Diabetes Mellitus,R587.1
  13. Improvement of Interleukin Profiles in Patients with Type 2 Diabetes Mellitus After Add-on Acarbose Therapy Independent of Glycemic Control,R587.1
  14. Efficacy and Safety of Biphasic Insulin Aspart 30 Once-daily Treatment in Patients with Type 2 Diabetes,R587.1
  15. The Blood Glucose Control and Influencing Factors in Type 2 Diabetic Patients with Oral Hypoglycemic Agents,R587.1
  16. The Analysis of Related Factors in Type 2 Diabetes with Depression,R587.1
  17. Effect of β-Casomorphin-5 on Blood Glucose and Oxidative Stress of Diabetic Rats,R587.1
  18. Study on the Protein Composition of Intestinal Flora in the Antibiotics Interfered Mice and the Bacteria-related Diseases,R446.5
  19. The Effects of Aerobic Exercise Training on Oxidative Stress and Ultrastructure of Pancreatic Organization in Diabetic Rats,R587.1
  20. Studies on Low-fat Ice Cream of Waxy Rice Starch and Its Derivatives As Fat Substrates,TS277

CLC: > Medicine, health > Chinese Medicine > TCM Internal Medicine > Modern medicine, internal diseases
© 2012 www.DissertationTopic.Net  Mobile