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The Changes and Influencing Factors of Blood-lipid and Plasma-glucose of Healthy Young People after Carbonaceous Fatty Meal

Author: LiaoChengHong
Tutor: LiJuXiang
School: Nanchang University
Course: Internal Medicine
Keywords: healthy young people body mass index carbonaceous fatty meal Lipid Metabolism Glucose metabolism
CLC: R541.4
Type: Master's thesis
Year: 2010
Downloads: 29
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Abstract


Objective: To investigate the lipid changes and influencing factors after carbonaceous fatty meal of different weight index of healthy young (average age:18.81±1.6), and to observe the differences of the effect after different fatty meal postprandial TG and PG and the differences of postprandial TG and PG between young people and middle-aged .Methods: (1) 112 healthy young people(average age:18.81±1.6) ate carbonaceous fatty meal(600kal heat, in which 27g fat (42%), 67g carbohydrates (50%), 24g protein (18%)) then measured fasting and postprandial TG and PG after 2, 4 and 6 hours. and made simultaneous measurement of fasting weight, height, blood pressure, heart rate and body mass index (BMI) at Basic condition. According to BMI, we divided three groups of specific criteria into overweight , normal, partial light.(2) Select 20 30-50 year old healthy adults (aged) to observe the effect of their age on postprandial TG, PG of different fatty meal. (3) 40 18-20 year healthy young people(young) ate carbonaceous fatty meal (the same before) and No carbon fatty meal(600kal heat, in which 36g fat (56%), 64g protein (44%) at random to observe the effect of on postprandial TG, PG of different fatty meal.Results: (1) The postprandial TG change of carbonaceous fatty meal of Healthy young people showed the trend from decline to recovery.PG presents increasing trend to recovery; there are significantly differences (P <0.05) of TG, TG-AUC among different weight index. Three curves are quite different, the higher BMI is, the fasting and postprandial TG at all time points is higher (P <0.05))(2)Men and women have no significant differences on TG, but the postprandial TG decline of female are more marked.(3)There are no significant difference on fasting and postprandial glucose at each time point.(p>0.05)weight index and TG0, PG0 show positive correlation. (TG0,r=0.317,p=0.001;PG0, r =0.247,p=0.009)(4)fasting plasma TG of middle-aged is slightly higher, fat load of postprandial TG increases at 3 time points after carbonaceous fatty meal, while the young group decreasing, the reaction curves are quite different.TG2、TG4、TG6 and TG-AUC are all significant higher than the young group.(5)2h, 4h of TG decrease after Carbonaceous fatty meal, 6h still below the fasting level; TG of fat fatty meal 2h increase, 4h gets peak, 6h declines and the curve characteristics are totally different.Conclusions: (1) The postprandial TG change of carbonaceous fatty meal of Healthy young people showed the trend from decline to recovery.PG presents increasing trend to recovery.(2) The BMI of healthy young people after carbonaceous fatty meal is higher, the TG after fasting and postprandial index is greater, overweight people of BMI have the possiblity of postprandial lipid metabolism disorder.(3)Age and sex are the main influencing factors to TG.(4)The effect of Carbonaceous fatty meal and No carbon fatty meal on postprandial TG is different. carbonaceous fatty meal can lead to postprandial TG levels healthy young decreases, postprandial levels of No carbon fatty meal of healthy young people increased, TG clearance speed is slow.

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CLC: > Medicine, health > Internal Medicine > Heart, blood vessels ( circulatory ) disease > Heart disease > Coronary arteries ( atherosclerosis ),heart disease (CHD)
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