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Corrosion myogenic cream in on traditional veterinary the topical prescription the corrosion Shengjisan the basis , after scientific groups , rigorous screening made ??of traditional Chinese medicine prescription . In this experiment revealed from the perspective of growth factor , post-traumatic stress corrosion myogenic cream to promote wound healing mechanism of action, provide a theoretical basis for the promotion and application of future corrosion myogenic cream . Wistar rats and KM mice , the test for the study, skin defects , a model of post - traumatic stress model is established on its back . Skin defects , a model of rat wound tissue of vascular endothelial growth factor ( VEGF ) and level of bFGFmRNA expression , hydroxyproline content , total protein content , histopathology and post-traumatic stress in mouse serum TNF-alpha , IL -6 and Cor. detection of indicators , initially revealed corrosion myogenic cream to promote wound healing mechanism . The results showed that: 1 . Corrosion myogenic cream can improve the the wound tissue of VEGF and bFGFmRNA level , which can contribute to vascular endothelial cells and fibroblasts proliferation and differentiation , indirectly mediated anti-corrosion myogenic cream to promote wound healing . 2 corrosion myogenic cream can stimulate fibroblast synthesis of collagen and total protein synthesis in the wound , so as to promote the growth of granulation tissue , improve wound healing . 3 . Preservative Shengjisan paste can promote early trauma Mouse IL-6 secretion , the latter inhibition of TNF - alpha , IL - 6 secretion , throughout inhibition Cor . Release . Description corrosion myogenic cream can reduce the body's stress response intensity, to avoid too strong stress on the body caused by injury . Observed by light microscopy of wound tissue found corrosion myogenic cream composed of fibroblasts and capillaries increased collagen arranged in neat rows , anti-corrosion myogenic cream can promote wound tissue fibroblast cell proliferation and capillary proliferation , increase the local supply of nutrients promote collagen synthesis , thereby promoting wound repair .
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