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Objective: To observe Tongqiao eyesight IV, for primary angle-closure glaucoma, the optic nerve of different interventions to protect the efficacy Methods: 60 patients with 108 primary angle-closure glaucoma patients with optic atrophy were used surgery and medications to control intraocular pressure were randomly divided into treatment A, B group and control A, B group . A control group were operative IOP , B group are medications to control intraocular pressure. The treatment group received traditional Chinese medicine Tongqiao No. Ⅳ eyesight , vitamin B1, vitamin B12 treatment ; control group were given vitamin B1, vitamin B12 treatment. Treatment results were statistically processed , the vision, vision , visual evoked potential compared before and after treatment aspects , P gt; 0.05 invalid , P lt; 0.05 is valid . Results : 1. Two kinds of intervention , the treatment group were significantly better than the control group (P lt; 0.05) 2. Before and after treatment, visual acuity, visual field mean light sensitivity , visual field defect, visual evoked potential P100 wave amplitude (μv ) , visual evoked potential P100 wave latency (ms) were improved , the difference was statistically significant (P lt; 0.05); treatment of group A and group B, the difference was not statistically significant (P gt; 0.05); vision control group before and after treatment , view an average light sensitivity , visual field defect, visual evoked potential P100 wave amplitude (μv), visual evoked potential P100 wave latency (ms) , the difference was not statistically significant (P gt; 0.05); were differences between group A and group B not statistically significant (P gt; 0.05). Conclusion : Herbal Tongqiao eyesight IV, for the treatment of different interventions under primary angle-closure glaucoma, optic atrophy have therapeutic effect on the optic nerve has a protective effect, and more effective than the control group ; through surgery or drugs to effectively control intraocular pressure after taking Tongqiao eyesight IV, can improve the patient's visual function. Possibly by improving the optic nerve retina 's blood circulation, improve nerve cell excitability , preventing retinal ganglion cells play a role in neuroprotection .
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