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Objective: through the application of ROI technology on the the 24h delay the flat-screen tomographic bone imaging to carried out the the semi-quantitative analysis of,, respectively, calculation and compare 4h with the the the 24h of the The uptake ratio of the suffering from / uninjured side radioactive nuclide (L / N value) and 24h/4h The uptake ratio of (TF value), the application ROC curve explore the the its on the the the of the clinical significance of of the spine single-hair lesions of benign and malignant the differential diagnosis of, and the the the performance of of the of the compare flat-screen scintigraphy with the the of the TF of the tomography imaging the value pairs the spine single-hair lesions of benign and malignant diagnostic. Method: collect in December 2009 ~ in September 2010 in the the first Hospital of the Shanxi Medical University, Department of Nuclear Medicine, carried out The whole body bone imaging shows there are the spine single-hair lesions of the in patients with 38 cases of, the of which men and 18 cases of, the female 20 cases of, average age of 49.71 ± 16.30-year-old (Age the scope of of 30 ~ 79-year-old). A the conventional after the the whole body bone imaging of, are line 4h and to 24h delay the flat-screen tomography imaging, 4h, the 24h the local flat-screen scintigraphy and local tomography imaging acquisition conditions is are the same, the flat-screen scintigraphy counts were acquisition the 500k, matrix for 256 × 256, Zoom1.0 ; The tomography imaging are acquisition 360 °, 6 ° / frame, 25s / frame, a a total of of 60 frames, an matrix of 64 × 64, the Zoom 1.0. Faults image reconstruction adopts OSEM iteration method, the OSEM reconstruction iteration the number of times 2, the number of a subset of 10, pre-filtering for the Hanning, cut-off frequency 0.9. All patients eventually were confirmed by been confirmed to the Pathology or clinical follow-up, pursuant to which the will be the in patients with is divided into the liang, vicious two groups of, benign group the 11 cases, and vicious group of 27 cases. The application of ROI technology lays out two groups of 4h and a 24h of flat-screen scintigraphy and tomography imaging cross - sectional concentrated poly stove,, respectively, calculation the two groups of of the 4h and 24h lesions District, radioactive Total the number of L 4h (L 4h ') with the L24h (L24h'); the subsequent will be its ROI replication (to guarantee ROI the same size) on the lesion on the or under the that the neighboring normal vertebral body the the corresponding parts of, get the The neighboring normal vertebral body the radioactive of the the the corresponding parts of to total counts N < sub> 4h (N 4h ') with N 24h (N24h'), repeat sketched the three times, whichever is average number of, According to the the formula TF = (L24h / N24h) ÷ (L 4h / N 4h ), respectively, calculation to out of the the the ratio of of the the ratio of the the planar imaging TF and tomography imaging TF '. If the the above-mentioned indicators is there are differences, then the in accordance with the relevant quantitative indicators, take advantage of receiver operating characteristic curve (receiver operating characteristiccurve, ROC curve) technology, compare ROC curve under the area of, analysis of the the indicators of the the the best of the diagnostic quantitative of in the the in in the bone imaging semi-quantitative analysis of, decided to of its the best diagnostic profession value point (discriminator diagnosis of benign and in the when the the This profession value the point is fetch, the the sensitivity of the of the malignant lesions, specificity of and accurate degrees of highest), and and calculate the of its the corresponding the the diagnosis of sensitivity of, specificity of. In Results: the 1. Flat-screen scintigraphy: the vicious group lesions 4h and 24h of the L 4h / N 4h , L24h/N24h value (2.02 ± 0.47,2.47 ± 0.73) than those in the benign group (1.62 ± 0.42,1.84 ± 0.46) was significantly higher, between the two groups the differences were has a significantly sexual significance (t4h = -2.46, p lt; 0.05; t24h = -3.12, p lt; 0.05); the TF value of the in malignant group (1.22 The ± 0.11) also obvious higher than the the the benign group (1.07 ± 0.06), the difference between the groups there are significantly sexual significance (t = -4.77, p-lt; 0.01). Vicious group in the a 24h of the L24h/N24h value than the the 4h, L 4h / N 4h in value was significantly higher (t = -2.25, the p-lt; 0.05), the while the the benign group the a 24h of the L24h/N24h value than the 4h, L 4h / N 4h value no statistically significant differences (t = -1.87, p> 0.05). L the 4h / N 4h , L24h/N24h, TF value receiver operating characteristic (ROC) curves the area under the, (95% confidence interval),, respectively, for the the 0.752 (0.538 0 .897), 0.838 (0.650 0 .095), 0.905 (0.763 0 .985), can be have to the TF value is the flat-screen Imaging in Diagnosing Spine the with single lesion of benign and malignant of the the best quantitative indicators. When the TF value is fetch 1.12 when the, the the single-hair lesions benign and malignant lesions the sensitivity of the of its diagnostic spine, specificity of the highest,, respectively, for the 100% and 77% respectively. 2. Tomography imaging: the vicious group lesions 4h and 24h of the L 4h / N 4h ', L24h/N24h', TF 'value (4.37 ± 1.20,5.57 ± 1.55 , 1.28 ± 0.09) than those in the benign group (3.35 ± 0.62,3.84 ± 0.95,1.14 ± 0.07) was significantly higher, between the two groups the differences were has a significantly sexual significance (t4h = -2.11, p-lt; 0.05; t24h = -2.71, p lt; 0.05, tTF = -3.48, p lt; 0.01). Vicious group to in the 24h the L24h/N24h 'value (5.57 ± 1.55) than the the 4h, L 4h / N 4h ' value (4.37 ± 1.20) was significantly increased (t = - 3.37, p lt; 0.05), while the benign group in 24h of the L24h/N24h 'value than the 4h, L 4h / N 4h ' Values ??There are no significantly differences in (t = - 1.96, p> 0.05). L 4h / N 4h ', L24h/N24h', TF 'value ROC area under the curve (95% confidence interval) is, respectively, for the 0.828 (0.657 0 < The / sup> .932), 0.896 (0.753 0 .970), 0.946 (0.820 0 .992), can be obtained the TF 'value is the bone faults Imaging in Diagnosing Spine single- hair lesions liang vicious of the the best quantitative of indicators, When the when the fetch 1.19, the the single-hair lesions benign and malignant lesions the sensitivity of the of its diagnostic spine, specificity of the highest,, respectively, for the 92.6% and 90.9%. Conclusion: 1. 24h delay the bone imaging semi-quantitative The analysis is performed on the the spine single-hair lesions the of benign and malignant the differential diagnosis of, has a the the a higher level of the clinical application of the value of. 2. When the the the delay faults bone imaging TF 'value is fetch to 1.19 when the, the the single-hair lesions-of benign and malignant the sensitivity of the of the its diagnosing spinal of information, the specificity degrees have the highest; and the was significantly higher than that to delay the the flat-screen bone imaging TF value to the the when the of the diagnostic performance in in fetch 1.12.
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