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Epidemiologic Survey on the Metabolic Syndrome and Related Factors in the Community of Luzhou

Author: SuYanHui
Tutor: ChenQiu
School: Luzhou Medical College
Course: Internal Medicine
Keywords: Community residents Metabolic syndrome Prevalence Predisposing factors Epidemiological investigation
CLC: R589
Type: Master's thesis
Year: 2011
Downloads: 32
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Abstract


Objective: To understand the situation of Luzhou City, community residents over the age of 20 the prevalence of the metabolic syndrome (MS), and explore its predisposing factors and prevention measures. Methods: A random overall sampling method, cross-sectional epidemiological survey of 2010 Luzhou Group Community for more than 20 years old, long-lived population, including ① survey: In general, past medical history, family history, smoking and drinking , physical activity, etc.; ② Physical examination: height, weight, waist circumference, hip circumference, blood pressure, etc., to calculate the body mass index (BMI) and waist-to-hip ratio (WHR); ③ Laboratory examination: fasting plasma glucose (FPG), total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol (LDL-c), liver function, renal function (including uric acid); ④ selected MS, 1 - two metabolic abnormalities by the normal control of the 30 cases, routine testing of fasting blood glucose ELISA method detects blood insulin (INS), free fatty acid (FFA), high-sensitivity C-reactive protein (hsCRP), tumor necrosis factor α (of TNF-α). 2004 China Diabetes Society (CDS) diagnostic criteria for metabolic syndrome were analyzed. Results: the Luzhou City (1) more than 20-year-old community resident male BMI, WC, WHR, systolic blood pressure, diastolic blood pressure, TG, LDL-c were significantly higher than women (P lt; 0.01), women than men HDL-c ( P lt; 0.01), also found that men uric acid (UA) levels than women. Community residents MS prevalence was 10.83% male and 11.80%, and 9.54% for women, gender comparison, the difference was statistically significant (P lt; 0.01). The various components of MS prevalence descending order for dyslipidemia, hyperglycemia, overweight and / or obesity, high blood pressure. Gender comparison: male hypertension, dyslipidemia, overweight and / or obesity prevalence was significantly higher than females (P lt; 0.01). (2) with increasing age, the prevalence of MS is gradually rising. Both men and women, 50 years of age, the prevalence of MS was significantly higher prevalence peaked at 60-69 MS, 22.03% and 18.72%. 57.80% of the total number of metabolic abnormalities, crowd gathering has a higher MS risk factors. (3) Logistic regression analysis showed that gender, age, BMI, WHR, alcohol consumption, diet, labor or physical exercise, family history of diabetes, blood uric acid levels and the incidence of MS is closely related to (P lt; 0.05), and the risk factors of MS ; independent risk factor for MS illness for age, BMI, WHR, diet; while regular exercise is a protective factor of MS. Drinking, family history of diabetes, blood uric acid associated with MS, but not an independent risk factor. (4) investigation of metabolic abnormalities accounted for 42.19%, 46.97% ≦ metabolic abnormalities, MS of 10.83%; the MS group age, BMI, waist circumference, WHR, systolic blood pressure, diastolic blood pressure, TG, FPG UA were significantly higher in the the metabolic abnormalities group and ≦ 2 kinds of metabolic abnormalities group (P lt; 0.01) higher than those without metabolic abnormalities group (P lt; 0.01) ≦ metabolic abnormalities group. Without metabolic abnormalities HDL-c group than ≦ 2 metabolic abnormalities group, MS group, the difference was statistically significant (P lt; 0.01). (5) 90 cases selected respondents ≦ metabolic abnormalities subgroups MS subgroup FFA, TNF-α, hs-CRP levels were significantly higher than non-the metabolic abnormalities Asian group (P lt; 0.01), MS subgroup FFA, TNF-α, hs-CRP levels were significantly higher than ≦ 2 metabolic abnormalities subgroup (P lt; 0.01). Conclusion: Luzhou Group Community MS prevalence is relatively high, may be related to their unique eating habits, should cause the unit in charge of great importance to effective interventions. Active lifestyle intervention to reduce the amount of oil and alcohol intake, increasing physical activity are the main measures to prevent MS.

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CLC: > Medicine, health > Internal Medicine > Endocrine diseases and metabolic diseases > Metabolic diseases
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