|
Undifferentiated spondyloarthropathy (undifferentiated spondyloarthropathies, uSpA) refers to a group with spondyloarthropathy clinical and radiological manifestations, but does not meet the established any kind of spondyloarthropathy. These diseases refers to the central axis and (or) peripheral joint involvement, has a tendency to familial aggregation, serum rheumatoid factor (RF)-negative and HLA-B27 was varying degrees related to the characteristics of a group of diseases, ankylosing spondylitis ( AS) as the prototype also includes undifferentiated the spondyloarthropathy (uSpA), psoriatic arthritis (PsA), reactive arthritis (REA), inflammatory bowel disease and arthritis (IBDA). uSpA is the spondyloarthropathy most common types of Objective: To explore the clinical features and follow-up undifferentiated spondyloarthropathy: 86 cases uSpA patients, both male and female groups were from the age of onset, age of diagnosis, the first symptom, clinical manifestations laboratory examinations were stratified comparison, analysis, 86 cases uSpA follow-up, follow-up of 0.5 years -9 years, 42 patients were followed up to, and delete the one developed in patients with psoriatic arthritis, this study for the rest of the follow-up 41 patients to be grouped into two groups, a group of 15 cases of clear clinical diagnosis of AS group, another group now the remains uSpA and complete remission (non-AS group) of 26 cases, respectively, from the age of onset , age of diagnosis, the first symptom, clinical manifestations, laboratory examinations stratified comparison and analysis. 1 male: female cases of 2.54:1, the men were significantly higher than women. The 2.uSpA course of inflammatory waist (or spine) pain, lower non-symmetrical synovitis were more common, followed by sausage toe (finger), attached to disease, alternating hip area pain. Between male and female, the female patients with inflammatory waist or spinal pain, sausage toe (finger) was significantly higher than in men (P lt; 0.05). Male patients with lower extremity non-symmetrical synovitis attached lesions with a high incidence in women (P lt; 0.05). 3.uSpA 38.4% of patients inflammatory lumbar pain (or spine) as the first, the most common clinical; between male and female comparison, women with inflammatory waist pain onset (or spine) starting significantly higher than men (P lt; 0.05), male hip area pain, ankle swelling and pain the first onset was significantly higher than women (P lt; 0.05) 4. USpA patients with HLA-B27 men than women positive rate. In 5.86 cases uSpA follow-up, follow-up of 42 patients, follow-up of 0.5 years -9 years, including the development of AS in 15 cases (36%), 16 cases (38%) still uSpA; 10 patients (24%) after treatment of symptoms disappeared completely; 1 (2%) the development of psoriatic arthritis. AS patients, 15 patients developed 3 years 4 cases, 27% (4/23), 3-6 years, 5 cases, accounting for 33% (5/11); 6-9 years of which 6 cases, accounting for 40 % (6/8). 6. USpA patients in the hip joint as the first symptom is easy to develop for AS, 33.3% in the hip joint as the first development is the possibility of AS. Course of disease in patients with uSpA hip attachment point lesions in patients prone to the development of AS, respectively, 53.3%, 66.7% the attachment points lesions, especially those with heel pain patients prone to develop AS, 53.3%. Conclusion: 1.uSpA, men, the incidence was significantly higher than women. (2) for the early onset of lower limb asymmetry arthritis, inflammatory waist or spinal pain, sausage toe (finger) patients as early as possible HLA-B27, sacroiliac joint CT contribute to the clinical diagnosis. 3 uSpA patients the development of ankylosing spondylitis, and should be followed up. 4 in the hip joint as the first symptom is easy to develop for the AS, clinical manifestations of attachment points lesions, especially in patients with heel pain easy to develop for the AS.
|