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Objective: coronary angiography and intravascular ultrasound exploration type 2 diabetes angina lesions characteristic of type 2 diabetes prevention and treatment of patients with angina pectoris help. Methods: meet coronary atherosclerosis heart disease angina clinical diagnostic criteria and diagnostic criteria for coronary angiography and coronary angiography simultaneously and intravascular ultrasound examination of 152 patients, according to 1999 World Health Organization diagnostic criteria for type 2 diabetes divided into diabetic group and the non-diabetic group, wherein the diabetic group, 56 cases, 96 cases of non-diabetic group. Two groups of patients should collect the following information: Clinical data including gender, age, height, weight, smoking history, drinking history, history of hypertension, coronary heart disease, cardiovascular disease, family history; biochemical data, including fasting blood glucose, postprandial 2h plasma glucose , total cholesterol, triglycerides, low-density lipoprotein, high density lipoprotein; coronary angiography image analysis results include; intravascular ultrasound image analysis results, including plaque nature of the lesion external elastic membrane area, lumen area, plaque block load, eccentric index, remodeling index, reconstruction incidence. Clinical data were compared two groups of patients, blood biochemical data, image analysis results of coronary angiography, intravascular ultrasound image analysis results. Results: The diabetic and non-diabetic patients with clinical features of patients were compared for age, height, weight, smoking history, history of hypertension, alcohol history, family history of coronary heart disease and cardiovascular history was no significant difference: the two groups of patients with blood biochemical examination comparison group of patients with diabetes fasting blood glucose (7.33 ± 1.14mmol / l vs 4.56 ± 0.47mmol / l P lt; 0.001) 2h postprandial blood glucose (13.09 ± 2.33mmol / l vs 5.87 ± 0.80mmol/lP lt; 0.001) and glycerol three fat (2.90 ± 0.94mmol / l vs 1.87 ± 0.57mmol / l P = 0.008) was significantly higher than non-diabetic group with statistical significance; former descending artery (LAD), circumflex artery (LCX), right coronary artery (RCA) , left main (LM) four major morbidity frequency point of view, the right coronary disease diabetes group frequently than non-diabetic group (62.5% VS 38.5% P = 0.004) were statistically significant; Judging from the cumulative blood count, three lesions in the diabetic group was higher than in non-diabetic group (44.7% VS 18.8% P = 0.001) were statistically significant, rather than single diabetic group was higher than the diabetic group (44.5% vs 19.6% P = 0.002) ; from the comparative degree of stenosis, severe stenosis in patients with diabetes onset frequency than non-diabetic group (42.8% VS 21% P = 0.004); parting from lesions on the comparison group of patients with diabetes mellitus type C lesions was higher than in non- diabetic group (46.5% vs20.8% P = 0.001) were statistically significant; nature from plaques compared diabetic patients calcified plaque and plaque rupture is higher than non-diabetic groups, respectively (23.2% vs 8.3% P = 0.010) (19.6% vs6.2% P = 0.011); quantitative analysis of intravascular ultrasound showed that the diabetic group luminal area (LA) than non-diabetic group (3.63 ± 1.01mm2vs4.62 ± 1.81mm2P <0.001 ) was statistically significant, but the plaque burden in patients with diabetes than non-diabetic patients (75.15% ± 8.46% vs 64.75% ± 11.56% P = 0.033); compared two groups of patients with vascular remodeling, remodeling index in patients with diabetes significantly lower than the non-diabetic group (0.96 ± 0.15 vs 1.00 ± 0.10 P lt; 0.001), was statistically significant, while negative remodeling diabetic group higher incidence (50.0% vs 23% P = 0.001), there was significant . Conclusion: Patients with type 2 diabetes mellitus right coronary artery disease angina high frequency. Type 2 diabetes and coronary artery disease in patients with angina to multivessel disease, a serious, complex lesions more common. 32 diabetic patients with angina plaque morphology mainly: calcified plaques rupture detection rate. 42 diabetic patients with negative remodeling of coronary phenomenon is more widespread.
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