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Background and Objective: changes in the structure and function of the arterial wall and cardiovascular disease morbidity and mortality are closely related. The change in the function of the vessel wall can lead to increased arterial stiffness, increased arterial stiffness has been shown to cause adverse cardiovascular prognosis. Order to study the characteristics of arterial elasticity, dynamic atherogenic index (AASI) due to its simple, repetitive and non-invasive characteristics more and more attention of clinical research, it is not a direct measure of the stiffness of a particular vessel segment, but rather a reflection of The overall arterial elasticity index, calculated from 24h ambulatory blood pressure values. The main purpose of this study the following two aspects: First, the analysis of impact the general population AASI factors; study AASI with the neck femoral pulse wave velocity (CFPWV) and radial artery augmentation index (rAI) match. Materials and Methods: Random sampling combined with cluster sampling method to select the Beijing area 36-85 years old untreated hypertensive population and blood pressure normal 335, 119 male, 216 female, mean age 66.94 ± 7.47 years . Questionnaire Droop method to collect general information and history; measurement of height, weight, waist circumference, hip circumference, and blood pressure, physical examination items; pumping biochemical tests of fasting blood line parallel 75g oral glucose tolerance test. Colin HEM-9000AI detector using radial artery tonometry measurement of left radial arterial pulse waveform; the application French Complior automatically measuring system for the determination of carotid - femoral PWV (CFPWV) as a reflection of the central the elastic arterial elasticity function indicators; Hungary production Mediech ABPM before and after treatement, detector-04 ambulatory blood pressure measured 24h blood pressure the daytime measurements every 20 minutes, night measurements every 30 minutes. SPSS 13.0 version statistical software for statistics and analysis of the data. Results: 1.AASI age, 24h average pulse pressure, CFPWV, rAI, showed a significant positive correlation (P lt; 0.001). 2. General population AASI the average of 0.53 ± 0.10, females AASI significantly higher than men (0.54 than 0.51, P lt; 0.05). Both men and women, AASI was positively correlated with age. The hypertension group AASI significantly higher than normal blood pressure group (0.59 ratio 0.52, P lt; 0.01). Using stepwise regression relationship between the entire survey population factors AASI based on considering the final independent variables into the model: age, height, 24h average pulse pressure, diastolic blood pressure, heart rate, CFPWV , rAl. The analysis showed: age, height, 24h average pulse pressure, diastolic blood pressure AASI values. Including age, 24h mean pulse pressure and AASI was positively correlated; height, diastolic blood pressure and AASI was negatively correlated; heart rate has nothing to do with AASI. Conclusion: AASI may be indicators of a new assessment of atherosclerosis; This value reflects arterial elasticity, carotid - femoral pulse wave velocity and reflects the overall flexibility of the entire arterial system rA Ⅰ match; adult AASI values ??by age and sex affect women AASI value than men; hypertensive population AASI values ??higher than normal blood pressure crowd; This value with age, pulse pressure, diastolic blood pressure lowering these traditional cardiovascular risk factors.
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