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Radiofrequency ablation of paroxysmal atrial fibrillation clinical analysis

Author: XiangJianQiang
Tutor: HanMingHua
School: Kunming Medical College
Course: Internal Medicine
Keywords: Atrial fibrillation Quality of Life Heart function Factors
CLC: R541.75
Type: Master's thesis
Year: 2011
Downloads: 137
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Abstract


Aim of the present study, the status of research methods, through self-questionnaire, S-F36 Health Questionnaire survey, echocardiography and other means of radiofrequency ablation in patients with paroxysmal atrial fibrillation before and after treatment and quality of life and impact of changes in cardiac function factors; assess radiofrequency ablation of paroxysmal atrial fibrillation efficacy and factors affecting the efficacy explore factors of atrial fibrillation recurrence after radiofrequency ablation, to further improve the success rate of radiofrequency ablation of atrial fibrillation. Method selected from September 2008 to October 2010 attached to a hospital in Kunming Medical College of Cardiology radiofrequency ablation for atrial fibrillation, 35 patients were followed up. Collection radiofrequency ablation in patients with atrial fibrillation before the general information, detailed medical history, ECG, ultrasound, etc., while applying SF-36 scales assess preoperative quality of life. Three-dimensional guidance downstream circumferential pulmonary vein ablation. Collected after 6 months follow-up in patients with ECG, ultrasound, surgical recurrence of such information, reapply SF-36 scale assessment of postoperative quality of life. Comparison of quality of life before and after surgery; heart function improvement; recurrence factor. Results 1 quality of life for the 35 cases radiofrequency ablation of paroxysmal atrial fibrillation, 70 questionnaires results were statistically analyzed using a paired t-test analysis of the quality of life before and after surgical treatment differences in each dimension, in addition to the body pain was not statistically meaning outside (t = 1.559, P = 0.125), the rest were statistically significant (Table 7). Two cardiac function by ultrasound examination, paroxysmal atrial fibrillation before and after radiofrequency catheter ablation of cardiac function (LVEF), the difference was statistically significant (t = -4.718, P lt; 0.001) (Table 5). Three factors of quality of life using multiple linear regression analysis showed: radiofrequency ablation of atrial fibrillation to improve the quality of life is not normal circumstances and lipids were negatively correlated with ejection fraction improvement and no recurrence was positively correlated; radiofrequency ablation recurrence and no recurrence compared to patients with atrial fibrillation ablation surgery to improve the quality of life is good; radiofrequency ablation improved ejection fraction as possible, the better to improve the quality of life of patients (Table 8,9). 4 of atrial fibrillation recurrence after radiofrequency ablation influencing factors Univariate analysis showed: Age (z = -2.025, P = 0.043), P wave dispersion (t = 2.193, P = 0.033), with or without hypertension (x2 = 6.286, P = 0.012) and left atrial diameter (t = -2.682, P = 0.012) were statistically significant, the rest was not statistically significant. Logistic regression for multivariate analysis: age, presence or absence of hypertension, and left atrial diameter was statistically significant (Table 10,11,12). 5 clinical observation in this study radiofrequency ablation of paroxysmal atrial fibrillation in patients with sinus bradycardia 2. Conclusions: 1. Circumferential pulmonary vein isolation technique can effectively treat atrial fibrillation, sinus rhythm, improve heart function and improve quality of life; 2. Age, hypertension, left atrial radiofrequency ablation of AF recurrence factors; 3 sick sinus syndrome (slow-fast) inappropriate radiofrequency ablation.

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CLC: > Medicine, health > Internal Medicine > Heart, blood vessels ( circulatory ) disease > Heart disease > Arrhythmia > Atrial fibrillation and atrial flutter
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