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Objective: Using Acoustic strong quantitative technical analysis fat liver study fat liver liver sound and strong characteristics, contrast ultrasound sound strong parameters, biochemical parameters for the diagnosis of fat liver, in order to investigate the ultrasonic strong parameters in fatty liver quantitative diagnosis and sub-degree application value analysis of fatty liver ultrasonic intensity parameter TCM-correlation, thus opening up a range of ultrasound studies to look for a new objective basis for TCM diagnosis of fatty liver. Methods: January 2010 to September 2010, the Sino-Japanese Friendship Hospital of routine ultrasound in patients with fatty liver of 200 cases, 30 cases of normal physical examination. Traditional ultrasound diagnosis of fatty liver patients were divided into mild, moderate and severe three groups (mild group (80 cases), 80 cases of the moderate group, severe group of 40 patients), and 30 healthy persons as a control group, Philips iU22 ultrasound diagnosis instrument, QLab-ROI acoustic quantification analysis software ultrasonic intensity of quantitative analysis of 230 cases of subjects selected from the right hepatic surface 1/6, 1/3, 1/2, 2/3, 5/6, right kidney in a very substance of the Ministry from the left liver surface 1.5cm at from the spleen on pole 2cm at the sampling location for the region of interest, draw echo intensity curve of each region of interest, the results into Excel database to obtain quantitative indicators, analysis of each indicator and fatty liver. Hitachi 7080 automatic biochemical analyzer, measuring 230 cases subjects alanine transferase enzyme (ALT), alkaline phosphatase (ALP), gamma-glutamyl transferase (GGT), aspartate transfer enzymes (AST) and glucose (GLU) value analysis of the relationship between value and fatty liver, sound intensity parameters and biochemical indicators of role in the diagnosis of fatty liver. TCM diagnostic criteria based on fatty liver, the tongue like the focus of observation, of the 200 cases of patients with fatty liver is divided into the liver Qi Stagnation, Spleen wet Yun certificate Damp volt card, phlegm the Accumulation card and phlegm the knot card five kinds syndrome type, TCM syndromes characteristics, research analysis of fatty liver fatty liver ultrasonic acoustic parameters and TCM type relationship. Results: 1. 1/6, the left hepatic from the right hepatic surface acoustic intensity value from the right hepatic surface 1/6 and 1/2, 1/6 and 2/3, 1/6 and 5/6 sound intensity ratio 1/6, away from the surface of the right liver and right kidney sound intensity ratio in the normal group, the fatty liver group among the groups there are significant differences (P lt; 0.05) from the right hepatic surface acoustic 2/3, 5/6 strong values ??from the the right hepatic surface of the 5/6 and right kidney sound strong ratio in severe fatty liver group and the normal group, light, moderate fatty liver group group there was a significant difference (P lt; 0.05). 2. Of ALT, GGT, AST / ALT values ??in the normal group, fat liver group each group were presence of a significant difference (P lt; 0.05), ALP values ??only in the normal group with fat liver group exist significantly with difference (P lt ; 0.05). 3 1/6 from the right hepatic surface acoustic intensity values ??with fatty liver indexing significantly related (correlation coefficient of 0.790, P = 0.000), from the right hepatic surface 1/6 points with 5/6 ratio of the sound intensity with fatty liver degrees are highly correlated (correlation coefficient of 0.801, P = 0.000), ALT and fatty liver indexing low correlation (correlation coefficient of 0.393, P = 0.000). Away from the area under the ROC curve of 1/6 of the right hepatic surface acoustic intensity value diagnosis of fatty liver was 0.990 from the right hepatic surface 1/6 and 5/6 sound intensity ratio diagnostic area under the ROC curve of fatty liver was 0.946, ALT diagnosis fatty liver area under the ROC curve of 0.774. 1/6 from the right hepatic surface acoustic intensity is higher than the value of the accuracy of the diagnosis of fatty liver from the right hepatic surface 1/6 and 5/6 ratio of the sound intensity and ALT. 4. Overall fatty liver spleen wet Yun certificate and Damp volts card more common liver Qi Stagnation mainly mild fatty liver, spleen wet Yun card mainly moderate fatty liver, Damp volt card, phlegm Accumulation card mainly to severe fatty liver, phlegm certificate mainly seen in mild fatty liver. Phlegm Yunjie card group from the 1/6, 1/3 of the right hepatic surface acoustic intensity value from the right hepatic surface 1/6 and 1/2, 1/6 and 2/3, 1/6 and 5/6 sound intensity ratio higher than the the spleen wet Yun permit groups (P lt; 0.05), phlegm Accumulation card group lower than the spleen wet Yun syndrome group (P lt; 0.05) 5/6 sound intensity values ??from the right hepatic surface. Away from the the right hepatic surface of the 1/6, 1/3 sound intensity values ??from the the right hepatic surface of the 1/6 and 5/6 ratio of the sound intensity with fatty liver TCM syndromes was weak positive correlation, the correlation coefficient were 0.152,0.143 , 0.141, P value is for 0.033,0.048,0.050. Conclusion: The sound intensity values ??of liver, liver, spleen, right kidney sound strength ratio can be objective, quantitative diagnosis of fatty liver, determine the degree of fatty liver disease. Biochemical indicators can be used as a quantitative indicator of the diagnosis of fatty liver and indexing. Ultrasonic intensity parameter of the diagnosis of fatty liver than biochemical indicators, the right hepatic near-field sound intensity value that is 1/6 of the right hepatic surface acoustic intensity value is a good indicator of the diagnosis of fatty liver, its value is 14.99dB , fatty liver diagnostic sensitivity of 95% and a specificity of 100%. Ultrasonic parameters with fatty liver TCM syndromes correlation ultrasonic intensity parameters as objective indicators and based on TCM diagnosis of fatty liver.
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