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Clinical evaluation of clinical features of cholestatic hepatitis and Integrative Medicine cholestatic hepatitis

Author: YangDi
Tutor: SunFengXia
School: Beijing University of Traditional Chinese Medicine
Course: Chinese and Western medicine combined with medical
Keywords: Cholestatic hepatitis Diagnosis Treatment Integrative Medicine
CLC: R259
Type: Master's thesis
Year: 2011
Downloads: 62
Quote: 0
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Abstract


[Objective] To investigate the clinical features of cholestatic hepatitis, including cause analysis, clinical symptoms, bilirubin, bile acids, serum enzyme variation. Contrast Western medicine treatment of cholestatic hepatitis and Western medicine treatment of Chinese and Western medicine combined with traditional Chinese medicine cholestatic party combined with the efficacy of the treatment, and to explore the treatment of cholestatic hepatitis optimization method. [Method] A retrospective analysis of Beijing Ditan Hospital nearly 10 years diagnosis as cholestatic hepatitis of medical records of 261 copies, analyze, summarize the clinical features; and a review analysis of Western medicine treatment and in Western medicine combined with (Western medicine treatment combined with traditional Chinese medicine silt gall side) 40 patients in the treatment of cholestatic hepatitis, compared to clinical improvement and the outcome of the situation. [Results] 82.76% of patients with acute cholestatic 17.24% for chronic cholestasis; the combined alcoholic hepatitis of viral hepatitis E and hepatitis E accounted for 46.74% of all cholestatic hepatitis, hepatitis B accounted for 18.39%, not points hepatitis accounted for 11.11%, 5.75% of the drug-induced hepatitis; skin itching or (and) in the the gray stools of patients accounted for 50.75% (P lt; 0.05) is the depth and jaundice. A total of 96 cases of Chinese medicine dialectical tongue relative performance of red, dark red, 84 cases (87.5%), yellow greasy moss, 82 cases (85.42%), in 14 cases (14.58%) white fur, pulse string of 85 cases (88.54%); The resistance network congestion in 87 cases (90.63%), in 83 cases (86.46%) and gallbladder damp heat stagnation and spleen deficiency in 47 cases (48.96%). TBiL peak to 395.96 ± 155.87 umol / L, the highest of up to 1095.9umol / L; TBiL peak at 20.47 ± 16.38 days, jaundice peak for 16.98 ± 10.54 days (3-68 days); GGT and ALP peak appeared in duration of 23.8 ± 22.37 days and 45.18 ± 22.10 days the TBA peak in 18.52 ± 17.32 Tian. CHO and TG peak time was 39.59 ± 18.66 days and 27.05 ± 16.48 days. Abdominal ultrasound showed enhanced liver echo diffuse gallbladder narrow, transparent sound. Liver pathology of the liver cells and portal area inflammation, liver cells and bile canaliculi cholestatic. 245 cases (93.87%) were clinically cured or improved, 3 patients died (1.15%), 13 cases (4.98%) left the hospital. Treatment: 8 weeks in group A (Western medicine treatment group) TCM syndrome integral decreased 26.99 ± 2.02 B group (in the combination therapy group) dropped by 28.13 ± 2.37; jaundice peak duration of group A 17.38 ± 11.41 days, B 12.73 ± 8.15 days; Group A of the average number of days of hospitalization 67.2 ± 11.24 days, B group 58.65 ± 12.38 days; average cost of hospitalization in group A 26142.07 yuan / person, group B 22247.28 yuan / person. The total efficiency of group A, 80% in group B and 95%. P Cholestatic hepatitis longer course, but the prognosis is usually good. Treatment: Integrative Medicine (Western medicine treatment combined with traditional Chinese medicine cholestatic square) therapy in the improvement of clinical symptoms, shorter hospital stays, reduced hospitalization costs were significantly better than Western medicine treatment group, should be popularized.

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