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Acupoint moxibustion treatment of chemotherapy-induced leukopenia clinical observation

Author: WangHui
Tutor: HuangJinZuo
School: Beijing University of Traditional Chinese Medicine
Course: Traditional Chinese Medicine
Keywords: Moxibustion Leukopenia Guanyuan Bone marrow suppression Granulocyte colony- stimulating factor Sea air hole Zusanli
CLC: R246.5
Type: Master's thesis
Year: 2011
Downloads: 142
Quote: 1
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Abstract


In this thesis, including the two parts of the literature review and clinical research. The topic of the literature review is chemotherapy-induced leukopenia mechanism of Chinese and Western medicine treatment research progress, reviewed the recent chemotherapy-induced leukopenia basic and clinical research progress at home and abroad, mainly from the pathophysiological mechanisms of leukopenia drug mechanisms and in recent years, Western medicine treatment are discussed. The comprehensive analysis of the chemotherapy drugs often leads to normal bone marrow hematopoietic cells was inhibited, and thus give rise to leukopenia, neutropenia affect the smooth progress of chemotherapy and the continuation of important factors, thereby affecting the efficacy and survival. Western medicine treatment is mainly based on the promotion of hematopoietic stem / progenitor cell proliferation and differentiation, and the release of mature granulocytes, more mature drug used in clinical recombinant human granulocyte colony-stimulating factor (rhG-CSF), and the relative system application specification and concurrent disease coping style, but expensive, short duration of action, easily repeated after stopping. Chinese medicine treatment advantage to holism governance of syndrome differentiation features and flexible treatment complements Western medicine treatment insufficient to achieve multiple therapeutic purposes, but the effect is slow, the lack of a large sample study, while the lack of disease for leukopenia machine. Part of clinical research, by analyzing the unique physiological characteristics, clinical symptoms and treatment of the law, leukopenia found with traditional Chinese medicine \Wei Yang, withstand exogenous pathogens, elevated white blood cell levels of efficacy. Objective: To observe the the moxibustion air sea, Guan Yuan, Zusanli efficacy of the treatment of chemotherapy-induced Ⅰ - Ⅱ degree leukopenia. Method: select chemotherapy Ⅰ, Ⅱ degree of leukopenia patients observed object, were randomly divided into two groups, the treatment group of 20 patients selected air sea, Guan Yuan, bilateral Zusanli each acupoint moxibustion 30 minutes, twice a day consecutive moxibustion 7 days. The control group of 20 patients with oral and blood pill, 5g, three times a day, day for seven consecutive days. Monitoring began treatment 3 days, 7 days, 10 days, 14 days, white blood cell count, and symptoms and quality of life before and after treatment scores, statistics of the incidence of infection. Efficacy criteria: treatment leukocyte gt; 4.O × 109 / L, and can be maintained until the withdrawal of effect one week after treatment, the clinical symptoms significantly reduced or disappeared was markedly; treatment after leukocyte lt; 4.0 × 109 / L, than before treatment increased (0.5-1.0) × 109 / L, and to maintain the efficacy of the treatment until one week after stopping the clinical symptoms improved effective; white blood cells after treatment rose lt; 0.5 × 109 / L, clinical symptoms do not improve as invalid. Results: 20 patients of the treatment group after treatment WBC gt; 4.0 × 109 / L, and treatment can be maintained until the withdrawal of effect one week after the clinical symptoms significantly reduced or disappeared, 17 markedly effective rate of 85% (17 / 20), higher than that of the control group, after treatment WBC lt; 4.0 × 109 / L, than before treatment increased (0.5-1.0) × 109 / L, and to maintain the efficacy of the treatment until one week after discontinuation of clinical symptoms improved 3, efficiency 15% (3/20), the total efficiency of 100%, the infection rate of 0%, higher than before to improve the quality of life. Conclusion: Moxibustion air sea, Guan Yuan, bilateral foot the Three Mile significantly improve chemotherapy-induced Ⅰ - Ⅱ degree leukopenia leukocyte level of patients, rapid onset of action, efficacy and stability, is worthy of further research and promotion.

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CLC: > Medicine, health > Chinese Medicine > Chinese medicine clinic > Acupuncture, acupuncture therapy > Clinical applications of acupuncture > Oncology
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