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【Objective】 irritable bowel syndrome (irritable bowel syndrome, IBS) Many scholars defined as psychosomatic diseases, its high prevalence, and to varying degrees, affect the quality of life of patients with IBS. The etiology and pathogenesis of IBS are so far not entirely clear, its treatment of multiple limitations. At home and abroad in recent years reported to conventional drug therapy combined with psychotherapy to achieve better efficacy, but the majority of the joint anti-depressant or anti-anxiety drugs for treatment. In this study, cognitive behavioral therapy combined with drug treatment, and a purely psychological treatment group, exploration alleviate the impact of the extent of the non-drug psychotherapy for patients with IBS symptoms. [Methods] 296 cases of IBS patients met inclusion criteria randomly divided into four groups: control group (n = 69) did not give any interventions; drug treatment group (70 patients) treatment according to disease type selection of different drugs ; psychotherapy group (78 cases) to take cognitive therapy and behavioral interventions; psychotherapy combined with drug treatment group (79 cases) in addition to conventional medicine using cognitive therapy and behavioral intervention. Of patients enrolled for the determination of IBS symptom score, and the Hamilton Depression Scale (HAMD, 17 items), Hamilton Anxiety Scale (HAMA, 14 items) was measured, and the quality of life for the IBS-QOL rating scale. Of enrolled patients were followed up once every two weeks, the integral on the clinical symptoms, depression and anxiety scale assessment of quality of life scale, and at the end of the entire course of treatment (12 weekends) determination. [Results] In addition to the blank control group, the other three Governing Law could improve the patient's symptoms, the overall efficacy of psychotherapy combined with drug treatment group. Drug treatment group total efficiency of 91% (of which 12 cases were cured, 25 cases markedly improved in 27 cases, 6 cases); psychotherapy group, the total efficiency of 89% (eight cases were cured, 20 cases markedly improved in 42 cases, 8 cases); psychotherapy combined with drug treatment, the total effective rate was 94% (of which 17 cases were cured, 44 cases markedly improved in 14 cases, 4 cases); assessment of the quality of life of the IBS-QOL, drugs groups, psychological groups, the reduction of medication plus psychotherapy group 1BS patients with the symptom index, the whole mental state improved. If you the HAMD gt; 17 the HAMA gt; 14 divided into whether depression and anxiety symptoms demarcation points. 205 cases of 296 patients with IBS with varying degrees of depression / anxiety. 205 IBS patients, 89 patients presented with symptoms of depression, 74 patients presented with symptoms of depression and anxiety, and 42 cases of patients with symptoms of anxiety. Joint drug-treated patients in the follow-up of patients completing therapy, psychotherapy, group psychotherapy in the treatment of 4 weeks, 6 weeks, 8 weeks and 12 weekends Hamilton Depression and Anxiety Scale scores significantly decreased compared with the drug treatment group and the control group, statistically significant (P lt; 0. 05). 12 weekends in the assessment of quality of life in addition to picky eaters, and other indicators were improved IBS-QOL scores than baseline was significantly higher. [Conclusion] medication, psychotherapy, psychotherapy combined with drug therapy can be improved to varying degrees of intestinal bowel syndrome patients with clinical symptoms and improve the patient's quality of life. Psychotherapy alone (the study of cognitive behavioral therapy) to change the clinical symptoms of IBS patients than the drug group psychotherapy combined with drug treatment group, suggesting that the uncertainty due to the pathogenesis of IBS, and the impact of factors than psychotherapy alone can alleviate clinical symptoms of IBS patients, but can not replace the role of drug therapy. Clinical psychotherapy combined with drug therapy has been widely confirmed, is worth promoting. In addition, in the course of the study found that psychotherapy in improving the clinical symptoms of the lateness of onset, and after 10 weeks of follow-up found that patients with IBS symptoms continued to improve, and the relapse rate than the drug group and psychological therapy combined with drug treatment are low, that mitigation role of cognitive behavioral therapy for IBS symptoms deserves further exploration.
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