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Objective : Clinical due to trauma , infection, or tumor surgery of congenital bone defects caused by the larger scope , it must be reconstruction . In this study, medical Osteoset calcium sulfate into mandible areas to observe medical Osteoset calcium sulfate in the jaw bone defects in effect , as well as medical calcium sulfate Osteoset provide basis for repair of bone defects . Method: 1. Experimental Research : Select four adult dogs , male or female , as subjects , surgical mandibular body formed dog criticality (20mm * 10mm * 3mm) bone defects (CSD). Using its own matching design defect left home medical calcium sulfate particles ; right hydroxyapatite particles into bone defects . 4 and 8 weeks respectively after clinical death dogs general observation , X -ray examination, environmental scanning electron microscopy , histological examination. (2) Clinical Research : Select from January 2010 to December 2010 during the application of medical calcium sulfate Osteoset filling mandible 9 patients ( 4 males and 5 females ) were followed up for 3-12 months to observe the wound healing and restorative materials rejection condition , the line X-ray examination . Result: an experimental study : four dogs all survived to the observation period. Incision area three days after the experimental side compared with the control side is slightly swollen but no infection, dehiscence , a week after the swelling subsided , postoperative general observation , x-ray , and Histopathology showed the experimental side material absorbs quickly, bone defects depression was significantly smaller , more mature bone tissue , control side material absorbs slow bone defects no significant changes in depression , new bone formation immature. 2 clinical study : 10 patients were followed up for bone defect repair have been better , no deformity and dysfunction , x -ray showed material in the fundamental absorption after 3 months , three months later than the postoperative bone mineral density density was significantly increased . During follow-up , 8 patients achieved healing Ⅰ incision , there is one case after a root zone area in recent months wound did not heal , a filling Osteoset spills and inflammation , through defect root canal treatment and dental rinse inflammation 6 weeks after wound healing dressing . Conclusion : Through experimental research and clinical application of two sets of reports were received postoperative mandibular defect filling, effective restoration of a good shape, helps restore chewing function . But the postoperative x-ray films showed : the repair of bone defects around teeth than other bone defects slow.
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