Dissertation > Excellent graduate degree dissertation topics show

Sol-gel Coated Molecularly Imprinted Polymers as Novel Stationary Phase for Stir Bar Sorptive Extraction of bisphenol A

Author: ShengNa
Tutor: HuQin
School: Nanjing Medical University
Course: Pharmaceutical Analysis
Keywords: Stir Bar Sorptive Extraction Pseudo template molecularly imprinted polymers Bisphenol A Sol-gel method Running water
CLC: TB383.1
Type: Master's thesis
Year: 2011
Downloads: 93
Quote: 0
Read: Download Dissertation

Abstract


Bisphenol A (Bisphenol A, BPA) is a common environmental estrogen, can interfere with the body's endocrine system and cause a variety of toxic effects of trace concentrations; very extensive and BPA use in daily life and industrial production, So simple, sensitive monitoring of BPA is very important. In the present study, we used the sol-gel method pseudo-template molecule to BPA imprinted polymer (Dummy molecularlyimprinted polymers, DMIPs) stirring rod coating material and apply its adsorption extraction tap water in trace BPA. Stir Bar Sorptive Extraction Technology (Stir bar sorptive extraction, SBSE) analyte extraction with adsorption material is on the surface of the coating attached to the stirring rod, the stirring rod itself while stirring to complete the treatment of the EUT enrichment with high sensitivity , less solvent consumption and easy operation. Existing commercially available stirring rod only non-polar coating materials, the adsorption capacity of polar substances very poor, and the lack of specific selective. To overcome this deficiency, we take advantage of the specificity of molecularly imprinted polymer adsorption, good specific adsorption of BPA the BPA pseudo template molecularly imprinted stir bar (DMIPs stirring rod) sol-gel method. The scanning electron micrograph of BPA pseudo template molecule is imprinted coating has a rough, a uniform surface structure, a coating thickness of approximately 57 μm. DMIPs, polydimethyl siloxane coating and BPA pseudo template molecular imprinting the infrared spectra of the coating showed that DMIPs been successfully embedded into the gel structure. Selective adsorption experimental data: stir bar sorptive extraction in mixed aqueous solution containing BPA and BPA structural analogues, DMIPs recoveries of BPA are biphenol 3 to 4 times, 4 - tert-butyl phenol 3 to 7 times, tetrabromobisphenol A 61 to 103 times. This fully demonstrates DMIPs stirring rod selective adsorption capacity of BPA. , DMIPs stirring rod extraction ability of BPA does not change with the increase of the concentration of structural analogues of the mixed solution BPA decreased, but remained relatively stable (response rate 88 ~ 98%), which show DMIPs stirring rod having strong anti-interference ability. Meanwhile, we compared the DMIPs stirring bar, a blank imprinted polymer (Non-imprintedpolymers, NIPs) for the coating of a stirring rod (NIPs stirring rod) and poly dimethyl siloxane (Polydimethylsiloxane, PDMS), as the coating stirring rod (PDMS stirring rod) the adsorption capacity of the BPA. The data show that the the BPA recovery rate of the DMIPs in stirring rod NIPs stirring rod 7 times, respectively, PDMS stir bar 24 times. Obviously DMIPs in stirring rod BPA adsorption capacity is far superior to the other two stirring rod. Finally, we optimize the experimental conditions the application DMIPs stir bar sorptive extraction, and successfully DMIPs-SBSE with high performance liquid fluorescence detection joint determination of the tap water of BPA. The standard curve of the analytical methods in BPA concentration 0.0228-0.456 ng mL-1 range linear correlation coefficient was 0.9994. BPA detection limit of 5.70 pg mL-1 (S / N = 3). We apply the method for determination of trace amounts of BPA in tap water has been satisfied with the results. BPA spiked recoveries in the range of 81.7? 98.2%, and the relative standard deviation of 10.2%.

Related Dissertations

  1. Fast Determination Method Research of Bisphenol A in Food Packing Material,TS206.4
  2. Synthesis and Performance Study of Bisphenol AP-based Polybenzoxazines,TQ320.1
  3. The Effects of Exposure to Bisphenol-a between Adolescence and Early Adulthood on Behaviors in Mice and Its Molecular Mechanism,R965
  4. The Study on Properties of Desulfurization and Denitrification by Mn/Al Catalysts,X773
  5. Sol - gel method p -type ZnO films,O484.1
  6. Technology and Properties of vanadium oxide thin films,TB383.2
  7. Synthesis and Characterization of Sb-doped SnO2-（CeO2-TiO2） Composite Thin Films Deposited on Substrates for Antistatic Electricity and UV-Shielding,TB383.2
  8. Preparation and Properties of Li4Ti5O12 as Anode Material of Lithium-Ion Batteries,TM912
  9. Research on Synthesis and Modification of Li3V2（PO4）3 as Lithium-ion Battery Cathode Material,TM912
  10. Preparation and Characterization of Electrochromic TiO2 Thin Films Dipped by Ce/Sm,TB383.2
  11. Study on the Preparion and Photo-catalytic Capability of Metal Ion Doped Nano Zinc Oxide,O643.36
  12. The Fabrication, Structure and Properties of SnO2/Sn/C Composites Anode Materials for Lithium Ion Batteries,TM912
  13. Determination of Organic Pollutants in Solid Sample by Hollow Fiber-based Liquid-phase Microextraction Combined Gas Chromatography-mass Spectrometry,O657.63
  14. Study on the Synthesis and Thermoelectric Properties of Ag Doped and Ag、 Cu Doped Ca3Co4O9,TB34
  15. The Study of the Sol-Gel Preparation of PZT Thin Film,TB383.2
  16. Construction and Application of CdTe Quantum Dots Based Electrochemical Biosensors for Catechol,Q813
  17. Studies on the Resistive Switching Properties of SrTiO3 Films,TP333.5
  18. Study on the Determination Method of Plasticizer and Bisphenol in Food Contact Materials,TS206.4
  19. Effect of Seed Layer on Microstructure and Porperties of BiFeO3 Thin Film,TB383.2
  20. Synthesis and Properties of 3-Dimensional Ordered Macroporous Tungsten Oxide Electrochromic Films,TB383.2
  21. Study on a New Optical Antifogging Nano-materials,TB383.1

CLC: > Industrial Technology > General industrial technology > Materials science and engineering > Special structural materials
© 2012 www.DissertationTopic.Net  Mobile