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Clinical Study on Medicinal Extract in the Treatment of Childhood Asthma Not-acute Episode Deficiency Syndrome

Author: XiaoNanXi
Tutor: YangHuaZuo
School: Guangzhou University of Traditional Chinese Medicine
Course: Chinese Academy of Pediatrics
Keywords: Paste Asthma in children Clinical Research
CLC: R289.5
Type: Master's thesis
Year: 2011
Downloads: 74
Quote: 1
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Abstract


Background Bronchial asthma is a chronic disease of the serious threat to public health worldwide, involving all age groups, especially children, the highest incidence of children is the most common chronic respiratory disease, a greater impact on children's health, learning and life, some persistent to adult asthma in children with asthma also become lifelong disorders. Of childhood asthma incidence rate in recent years as the socio-economic progress gradually increased for the first time in 1990, the National Children's asthma epidemiology survey results show that the incidence of childhood asthma was 1.15% in 2000, the second epidemiological survey The incidence rate increased to 2.1%. In addition similar to other atopic diseases, such as allergic rhinitis, atopic dermatitis, eczema and other diseases, support for these diseases share a common environment and genes incentives. Modern medicine in the analysis of the role of the epithelial cells and found that TSLP (thymic stromal cells to produce the hormone) in the pathogenesis of atopic dermatitis and asthma, both common barrier obstacles mechanism exists, and thus raised the body both inside and outside the same barrier the same kind of disease, \Chinese medicine as early as thousands of years ago, the height of the proposed the lung and fur mutual relationship summarized theory - \in the interaction is not limited to the link between lung and muscle tables in the anatomical sense, is manifested as physiological and pathological phenomena of lung activity and therefore, we are in a strong theoretical guidance of Traditional Chinese Medicine prevention and treatment of asthma in clinical practice, and did not use traditional Chinese medicine decoction is portable and taking herbal paste formulations, summed up the Guangdong Provincial Hospital of childhood asthma specialist use of TCM herbal paste formulations in children with asthma acute exacerbation of deficiency the clinical efficacy of the treatment before and after comparison test design, observation of children with asthma exacerbations, episodes of the degree of the usual symptoms and improved quality of life, objective evaluation of the clinical efficacy of the herbal paste treatment. In this paper, the mechanism of the pathophysiology of asthma from modern medicine, treatment methods and means of the traditional Chinese medicine theory several aspects of asthma due to illness machine, the research progress of Chinese medicine treatment summarized at home and abroad on pediatric asthma research progress; these findings consensus is When the overall treatment is the treatment of the disease, staging permit differentiation, both Western medicine and complementary. Use Paste the author under the guidance of the mentor Professor Yang Huacui in Shanghai Traditional Chinese Medicine Hospital to treat asthma experience based on the use of their own before and after the controlled trial design and statistical means, observed Paste the treatment of pediatric asthma, and efficacy of scientific and objective evaluation, the hope the TCM theory can deepen the understanding of the disease, find more precise and effective prevention and treatment of asthma in children in Chinese medicine for the next step to improve pediatric asthma overall Treatment of law to make a useful exploration, further improve the clinical control of asthma in children, and to improve the quality of children's lives. The aim of the present study was designed clinical trials observed Paste efficacy of treatment of children with asthma acute exacerbation of Deficiency Syndrome in the ointment side - objective evaluation of clinical efficacy for the treatment of asthma in children. Method by itself before and after the controlled clinical trial design, observed 30 cases of patients met the research requirements, taking in aspects of the the TCM clinical symptom scores before and after treatment creams square and signs of improvement, the number of clinical seizures and the use of rescue medication times and implementation of children and parents to fill out the evaluation of the C-ACT scale. And children with asthma control follow-up assessment. Were also the result by the square of cream treatment, children with significant difference in improvement in the TCM clinical symptoms of their own before and after integral signs; clinical exacerbation frequency and the number of use of rescue medication, activity limitation, symptoms impact, C-ACT score statistically significant. Spleen Yifei conclusion grounds virtual Peiyuan legislative principles made the cream can significantly improve the clinical symptoms of asthma in children. Merger and suffering from allergic rhinitis, eczema and other diseases can also achieve a therapeutic effect, raise the level of the overall treatment of children with asthma.

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