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Objective To analyze the Kawasaki (Kawasaki disease, KD) concurrent coronary artery aneurysms (Coronary artery aneurysm, CAA) risk factors and prognosis . Methods Retrospective analysis of Children's Hospital of Chongqing Medical University from January 1993 to December 2009 a total of 17 years during the 3902 cases hospitalized children with KD clinical data on the occurrence of coronary artery lesions with factors such as gender , age, fever , IVIG use duration , white blood cell count (WBC), hemoglobin (Hb), platelet count (PLT), erythrocyte sedimentation rate (ESR), C -reactive protein (CRP), serum albumin, creatine kinase (CK-MB ) , etc. count data χ2 test, t-test measurement data , the single factor analysis of the variables selected multivariate Logistic regression analysis ; 46 cases for follow-up after the disease CAA children 1 month, 3 months, 6 months , 1 year , 2,3,4,5 years , five years or more CAA recovery situations and different doses of intravenous immunoglobulin (Intravenous injection immune globulin, IVIG) long-term efficacy of χ2 test. Results ( 1 ) Univariate analysis showed that gender, age, fever , IVIG use duration , Hb, ESR, serum albumin and KD concurrent CAA related (P lt; 0.05), the single factor analysis of the above factors as screening further line of argument multivariate analysis showed that Hb, ESR, IVIG duration when used concurrently with KD CAA was independently associated (P lt; 0.05), while gender, age, fever , serum albumin and KD independently associated with non- concurrent CAA (P gt; 0.05); (2) small CAA, medium CAA, GCAA retraction time gradually extended (P lt; 0.05), age and dose of IVIG CAA retraction time no statistically significant correlation (P gt; 0.05 ) . Conclusion Hb lt; 100 g / L, ESR gt; 50mm / h, IVIG use duration gt; 10 days is the KD CAA concurrent risk factors ; CAA CAA retraction time and related to the size and age and unrelated to the dose of IVIG .
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