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Objective: To investigate the clinical value of multislice spiral CT (MSCT) to determine the acute and chronic phase of deep venous thrombosis (DVT), as well as acute and chronic phase DVT MSCT signs and prothrombin time (PT), activated partial thromboplastin time ( APTT), fiber Fib (FIB), clotting time (TT) correlation. Materials and Methods: A retrospective analysis of 37 patients with digital subtraction angiography (DSA) confirmed DVT cases, first of all, according to the course of the disease will be divided into acute and chronic phase, two weeks, and within two weeks of the acute phase of DVT 2 weeks DVT chronic phase of DVT, the course of more than two weeks of acute hair also attributed to the acute phase but in two weeks, observe the blood vessels and blood clots in the the MSCT enhanced image morphology, thrombus distribution of soft tissue and the performance of the collateral vessels, thrombosis parts enhanced image control MSCT measurement unenhanced axial images thrombosis CT values ??and standards thrombus CT value and standard deviation of two independent samples t-test, p lt; 0.05 was considered statistically significant. Secondly, according to the thrombus morphology on MSCT, thrombosis ranges, the thrombus CT value packet, using two independent samples t test was used to compare between groups PT, APTT, FIB, TT difference, p lt; 0.05 difference was statistically significant. Results: ① grouped according to duration of the acute phase DVT18 cases, including three cases of more than two weeks duration, but in two weeks of acute hair MSCT mainly venous lumen central filling defect within the lumen to expand thrombosis was continuous distribution, soft tissue swelling, \increased collateral circulation, superficial vein tortuosity. MSCT scan of acute and chronic phase thrombosis CT values ??were the 59.26 ± 11.89HU and 37.42 ± 9.46HU,, u = 20.92, p lt; 0.05, the difference was statistically significant; standard deviation of the acute and chronic phase thrombosis were 12.46 ± 3.43 and 8.34 ± 2.96, t = 4.27, p lt; 0.05, the difference was statistically significant. ② According MSCT enhanced thrombus morphology on the image is divided into a central filling defect group and eccentric filling defect group, 23 cases and 14 cases respectively; at thrombotic distribution divided into the continuity of the distribution group and segmental distribution group, respectively, 19 cases and 18 cases, if both packet attributed mainly group; measurement MSCT scan axial images thrombosis CT value using the WPS office spreadsheet software mapping to obtain the CT value of the intersection of the acute and chronic phase DVT thrombosis thrombotic CT value 53.6HU, The ≥ 53.6HU has 24 cases, the CT value of lt; 13 cases 53.6HU. The center of the filling defect group PT, APTT, FIB values ??than those of eccentric filling defect group, the difference was statistically significant (t = 4.95,3.27,4.05, p lt; 0.05); TT value comparison the difference was not statistically significant (t = 0.53, p gt; 0.05). Thrombosis was continuity of the distribution group PT value is compared with the segmental distribution group, the difference was statistically significant (t = 6.10, p lt; 0.05); APTT, FIB, TT value comparison the difference was not statistically significant (t = 1.88,1.46 , 1.95, p gt; 0.05). Thrombosis CT values ??≥ 53.6HU group PT, APTT, FIB, value than that of CT values ??lt; 53.6HU those differences statistically significant (t = 3.97,6.21,6.14, p lt; 0.05); TT values ??was not statistically difference (t = 1.99, p gt; 0.05). Conclusion: In this group of 37 patients with lower extremity DVT, acute and chronic phase MSCT signs of DVT has partial cross, but have their own characteristic performance of MSCT scan the thrombus CT value and standard deviation of measurement can be inferred acute and chronic thrombosis, MSCT judge of deep venous thrombosis with acute and chronic clinical value and MSCT signs of acute and chronic phase DVT and PT, APTT, FIB some correlation, TT no significant correlation. MSCT and coagulation and fibrinolysis indicators both checks, can improve the accuracy of thrombosis with acute and chronic judge to provide a reliable basis for clinical treatment plan formulated.
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