Dissertation > Excellent graduate degree dissertation topics show

Morphological analysis of the structure of the brain magnetic resonance image

Author: LiJin
Tutor: ChenHuaFu
School: University of Electronic Science and Technology
Course: Biomedical Engineering
Keywords: MRI brain morphometry local Gyrification Index cortical thickness
CLC: R445.2
Type: Master's thesis
Year: 2011
Downloads: 92
Quote: 0
Read: Download Dissertation

Abstract


Brain science is the research front of life science, mixing together many disciplines and technology. The rapid development of magnetic resonance imaging (MRI) becomes a important tool for the study of brain science, it promotes the understanding, protecting, developing of brain. Based on the various image analysis technology, we can detect and research brain in many different aspects. Among them, brain mophometry can reflect the information of brain structures directly, and has a wide application in clinical use. This paper use the method of brain morphometry to study the high resolution structure MRI in clinical and cognitive field. Particularly, we discussed the possible pattern of variability of brain cortex. The main work is as follows:1. Study of functional magnetic resonance imaging (fMRI) revealed the "cortex-limbic system" pathophysiology model in social anxiety disorder (SAD) and numerical results show that amygdala play a important role in this model. But there is few study of the model using structure MRI. This paper first investigated possible pattern of variability of brain cortex using local Gyrification Index (lGI). Compared with the normal control, patients with SAD show significantly decreased lGI in superior parietal gyrus, and the mean lGI of the area correlated inversely with the severity of anxiety symptom. In addition, the result prove reduced left amygdala volume correlated inversely with the primal severity of anxiety symptom in SAD. These results may provide a new evidence for the "cortex-limbic system" model.2. The game of Chinese chess involves many aspects of high-level cognition. Previous study indicates that high-level cognition processes is associated with the brain’s functional architecture revealed by fMRI. Whether such long-term practice has the effect of cortical structure has not been investigated. We used high-resolution MRI to assess cortical thickness in 17 Chiness chess master players and 17 matched controls. Between-group differences show a whole cortical thickness decreased in masters group including the precuneus, prefrontal cotex and paracentral cortex. Higher intensity of training is associated with thinner cortex in bilateral precuneus, left hemisphere prefrontal cortex. These results provide a structural evidence for cortical plasticity associated with long-term practice in high-level cognition.

Related Dissertations

  1. Study of MRI Diffusion-weighted Imaging in the Diagnosis of Lymphadenopathy and Evaluation after Radiotherapy,R445.2
  2. The Application Study of Delay-enhanced MRI in Normal Cartilage and Phase Ⅰ and Ⅱ of Cartilage Lesions of the Knee,R445.2
  3. Application of Functional MR Imaging in Diagnose for Prostate Cancer,R737.25
  4. Research on Spine MRI Image Segmentation Based on Knowledge,TP391.41
  5. Based on DCE-MRI of computer-aided diagnosis of benign and malignant breast lesions studied,TP391.7
  6. Measurement of Cortical Thickness and Its Application,TP391.41
  7. The Application of Dual-source Computed Tomography to Evaluate the Global Left Ventricular Function in Aortic Valve Replacement,R445.2
  8. Study on Evaluation of Comprehensive Benefit of MRI Equipment in County-level Hospital in China,R197.3
  9. MRI Study of the Third Ventricle Volume and Width Inhealthy Chinese Adults and Compare to Width in Hydrocephalus,R445.2
  10. Bregman Iteration Method and Its Applications to Sparsity Problems,TP301.6
  11. Segmentation of Magnetic Resonance Brain Tissues Image Based on Support Vector Machines and the Level Set Method,TP391.41
  12. Research of Segmented K-Space Imaging in MRI,TP391.41
  13. The Research of Segmentation on MRI Brain Image,TP391.41
  14. Construction of an in Vitro Visualization Model of Human Normal Uterine Arterial Vascular Network,R322
  15. MR Imaging of Cruciate Ligament and/or Meniscal Tears,R445.2
  16. Synthesis and Medical Application of Functionalized Carbon Nanotubes and Hyperbranched Polymers,R943
  17. The Development of Transceiver for Magnetic Resonance Imaging Spectrometer,R318.6
  18. Clinical Application of Contrast-enhanced Whole-heart Coronary Magnetic Resonance Angiography at 3.0T,R445.2
  19. The High-Resolution Microscopy Coil MRI for Orbit: Preliminary Study,R445.2
  20. Application Value of MRI to the Clinical Treatment of Carpal Tunnel Syndrome,R688
  21. Clinical Study on Comparation Between CT and MRI Images of Lumbar Disc Herniation,R681.53

CLC: > Medicine, health > Clinical > Diagnostics > Diagnostic Imaging > Magnetic resonance imaging
© 2012 www.DissertationTopic.Net  Mobile