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Researches on the Processing and "Tongue Numbing" Evaluation for Pinelliae Rhizoma and Aconiti Radix

Author: HuangYongLiang
Tutor: SunLingGenï¼›WuChunJie
School: Chengdu University of Traditional Chinese Medicine
Course: Pharmacy
Keywords: Toxic Chinese medicines Pinellia Radix Concocted Ma tongue characteristics Evaluation Method
CLC: R283
Type: Master's thesis
Year: 2011
Downloads: 186
Quote: 0
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Abstract


Breit and Radix is ??representative of the toxicity of traditional Chinese medicine, health products all have their strong mucous membrane irritation, manifested as \\However, a slight sense of how to define Ma tongue? Unavoidable human factors, as well as safety and health issues, making it difficult to get pharmaceutical quality assurance. This study is associated with the material basis of Ma tongue, extraction and separation of the first and Radix Pinellia different ingredients, and to evaluate the respective irritant, preliminary study two kinds of toxic material basis of traditional Chinese medicine Ma tongue and mechanism: by trying eye irritation test, etc. four ways to evaluate two kinds of Chinese medicine and its processed products Ma tongue level, analyzing their appropriate evaluation methods; while concocting a variety of chemical constituents during the measurement in order to determine the appropriate endpoint concocted foundation. Two types of toxicity tests initially proved the material basis of traditional Chinese medicine Ma tongue, Pinellia contains a special calcium oxalate crystal and Aconitum alkaloids in their respective classes may irritating ingredients; irritation evaluation test results show that the rabbit Eye irritation test can evaluate both Ma tongue characteristics, but is not sensitive to weak irritant: chorioallantoic membrane staining test method can be used to evaluate the strength of Pinellia Ma tongue; invertebrate test can evaluate Breit and Radix Ma tongue strength but operability is not strong, it is difficult application. Radix Pinellia and concocted a variety of ingredients during the change has its own rules, safety, objective and controllable grasp concocted finish quality is essential for ensuring Pieces: This topic while Breit and cooked Radix Ma tongue characteristic changes during study . The results showed that with the increase in processing time, irritation is decreasing. Rabbit eye irritation test results can indicate irritation from strong to weak trend, but can not accurately determine the \Therefore the establishment of this method is based on criteria of Pinellia concocted end, instead of the traditional tasting method can improve the standard of objectivity, quality assurance Pieces: Not found accurate assessment Chuanwu Ma tongue different degrees of biological assessment methods can be considered artificial taste evaluation techniques to create a new criteria. The topics were two kinds of traditional Chinese medicine and related Ma tongue preliminary study, has made some progress, pending further study and confirmation.

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CLC: > Medicine, health > Chinese Medicine > Of Pharmacy > Chinese medicine processing,preparation
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