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Purpose:In this study, systemic lupus erythematosus activity index SLEDAI, SF-36 scale and the fatigue index scale FSS, the amount of points hormones, hormones, and other side effects of the score sheet evaluation, the use of extracts from Herba Siegesbeckiae Chinese medicine treatment of active SLE, explore Herba Siegesbeckiae SLE intervention and assistance in reducing side effects of withdrawal of hormones and reduce the role of hormones.Material and method: Will be eligible subjects were randomly divided into control group and experimental group and control group treated with conventional western medicine, the experimental group on the basis of conventional western medicine to Herba Siegesbeckiae extract treatment, SLE patients with SLEDAI activity index, hormone dosage and quality of life the impact of the initial period of 6 months were observed Herba Siegesbeckiae extract complex treatment of SLE disease activity, reduce hormone withdrawal, reduce side effects of hormones and improve the quality of life in.Results:In this study the use of systemic lupus erythematosus disease activity index (SLEDAI) standings, hormones score (GCS) table, hormonal side-effects score (GCSES) table, the fatigue index (FSS) questionnaire, SF-36 Inventory of swine Siegesbeckiae extract treatment of mild to moderate active SLE randomized controlled trial started, the results showed two groups of hormones points 20 weeks, the difference was significant (P <0.01), FSS points at we。ek 24 compared the two groups, the difference significant (P <0.05), more than two groups at all time points before and after the effect of scale was no significant difference (P> O.05), small sample size which may be relevant. Two groups of points based on trends seen on the basis of conventional western medicine with Herba Siegesbeckiae extract capsules in improving patients with mild to moderate SLE SLEDAI points, to reduce side effects and improve the quality of hormones has a good effect.Conclusion:Extract Herba Siegesbeckiae developed capsule, with clinical glucocorticoid hormone treatment of moderate active SLE is effective. Choice of systemic lupus erythematosus disease activity index (SLEDAI) standings, hormones score (GCS) table, hormonal side-effects score (GCSES) table, the fatigue index (FSS) questionnaire, SF-36 scale, etc., as the evaluation of SLE indicators of disease activity and efficacy. Preliminary results demonstrate Herba Siegesbeckiae extract capsule SLE effective security can improve the clinical symptoms and reduce the hormone dosage, reduce the side effects of hormones, especially the recent improvement of SLE patients with symptoms and improve the quality of traditional Chinese medicine has a good effect.
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