Dissertation > Excellent graduate degree dissertation topics show

New triazine cyclophane pyridine cyclophane synthesis of research

Author: LiuYanFeng
Tutor: HuaChengWen
School: Northwestern University
Course: Organic Chemistry
Keywords: supramolecular chemistry triazine-based cyclophane pyridinophane synthesis characterization
CLC: O621.25
Type: Master's thesis
Year: 2009
Downloads: 104
Quote: 2
Read: Download Dissertation

Abstract


Supramolecular chemistry is a cross subject in chemistry, which is contact with material sciences and information sciences, life sciences. It is at the forefront of contemporary chemistry. In organic chemistry and supramolecular chemistry, the design, synthesis and application of artificial macrocyclic compound with novel shapes and geometries have been continued to be of interest. The basic feature of supramolecular chemistry comes into being the host-guest complex in the basis of molecular recognition. As the most representative objects of host compounds, crown ethers, cyclodextrins, calixarenes, cyclophanes have achieved remarkable results in the main body of basic research and many areas.As a sort of important macrocyclic compound, the properties of cyclophane have been researched by chemists extensively. It is a kind of circular compound connected by methylene bridged and aromatic ring. There is a hole in the molecule and in which the aromatic ring is placed sideway, so the molecule is hydrophobic. As an artificially simulated enzyme, cyclophane can capture different organic molecules to form host-guest inclusive complex according to the differences of the ring shape, size and electrostatic effect. Currently, one direction of cyclophane research areas is changing the ring skeleton of the cyclophane structure, including the use of certain heterocyclic compounds such as pyridine, imidazole, benzimidazole, triazine, thiophene instead of benzene ring and with hetero-atoms S, N, O instead of methylene-bridged to form heterocyclophanes. The introduction of heteroatom changed the structure and the bonding performance of the cyclophane, which can fit different substrate molecules.This thesis did research on the synthesis of triazine-based cyclophane and pyridinophane. In part 1, a brief introduction of supramolecular chemistry and cyclophane chemistry, the development of pyridinophane, midazolophane, indolophane, tetrathiafulvalene cyclophane, benzotriazolophane and triazine-based cyclophane have been provided as well as a presentation of actuality and the foreground of the cyclophane research; In part 2, synthetic methods and the characterizations of several novel triazine-based cyclophanes were presented. By a fragment coupling approach, a number of hetero atoms -bridged triazine-based cyclophanes have been synthesized through cheap raw materials, an unusually high yielding and efficiency in gentle condition; In part 3, the synthetic method of pyridinophane was reported, the isophthalic acid and isophthalyl chloride were synthesized taking m-xylene as the raw material. With isophthalyl chloride and the Na salt of acetoacetate ester, the isophthaloyl-di-acetic ester was synthesized, finally two novel pyridinophane were obtained by Hantzsch synthetic method.

Related Dissertations

  1. Studies on the Synthesis and Technology of Dipentaerythritol and Its Derivative,TQ223.164
  2. Synthesis and Characterization on Semi-Aromatic Polyamides Containing Benzoxazole Units,O633.5
  3. Hydrothermal Synthesis of Oxide Hollow Spheres,TB383.4
  4. The convergence of mathematics teaching in primary and secondary schools under the new curriculum with the problem representation,G633.6
  5. Video Coding Research Based on Texture Characteristics,TP391.41
  6. Poetic alienation : graphics,J506
  7. Urothermal Synthesis, Structure and Characterization of Functional Coordination Polymers,O631.3
  8. The Total Synthesis of a Flavonoid Glycoside Apigenin-7-O-β-D-glucuronide,R284.1
  9. Atovaquone analogues Design, Synthesis and antitumor activity of,R914
  10. Studies on Synthesis, Characterization and Properties of Fe-V Co-doped TiO2 Catalyst,O614.411
  11. Synthesis and Seperation of 1,1’-binaphthol,O625.3
  12. Characterization of Corn Lectin and Application to Screen of Growth-promoting Bacteria from Corn Rhizosphere,S513
  13. Flexible,rigid,Synthesis and characterization of mixed ligand complexes,O621.1
  14. Synthesis and Performance Study of Bisphenol AP-based Polybenzoxazines,TQ320.1
  15. Study on the Synthetic Process of Vat Pink R,TQ616.2
  16. Health-based and Ecological Risk Assessment of Contaminated Sites,X820.4
  17. Preliminary Research on Characterization of Thermophilic Protease Pasey and Helicase Htc16,Q814
  18. Cloning and Expression of Xylanase Gene from Thermobifida Halotolerans YIM 90462~T,Q78
  19. Study on the Mechanism of Night Temperature to Grain Filling of Inferior in Rice,S511
  20. Gold-catalyzed Addition Reaction of Sulfonates and Alkynes and Study of Synthesis and Bioactivity of (E)-3-phenyl-substituted Acrylic Acids,R914
  21. Isolation and Characterization of Carbendazim-Degrading Strains, Cloning and Expression of the mheI Gene,X172

CLC: > Mathematical sciences and chemical > Chemistry > Organic Chemistry > Organic Chemistry general issues > Properties of organic compounds > Chemical properties of organic reactions
© 2012 www.DissertationTopic.Net  Mobile