Dissertation > Excellent graduate degree dissertation topics show

A Study of Wallerian Degeneration in Cortico Spinal Tract after Cerebral Infarction by fMRI

Author: LeiSongZuo
Tutor: LouMingWu
School: Zunyi Medical College,
Course: Medical Imaging and Nuclear Medicine
Keywords: cerebtal infarction acupuncture wallerian degeneration functional magnetic resonance imaging diffusion tensor imaging
CLC: R445.2
Type: Master's thesis
Year: 2011
Downloads: 15
Quote: 0
Read: Download Dissertation

Abstract


Objective:To investigate the development of wallerian degeneration after cerebral infarction by DT、MRS.To evaluate the relation between wallerian degeneration and motor recovery of stroke patients and try to guide the prognosis.Metheds:Patients with a recent unilateral cerebral infarction were chosed, male 16, female10, age31-78,mean age61.5; Volunteers were chosed, male 18,female 12,age 19-72,mean age 55.9. There were no significant differences between groups on gender and age (P>0.05) The volunteers were performed Serial DTI and MRS scans for one time.The patients were performed Serial DTI,FLAIR and T2WI(TRA、SAG、COR) scans for four times which were on 1W、1M、3M and 6M. In addition,the NIHSS and BI were measured during each time.FA、ADC and MRS were examined at infarction area and cerebral peduncle.The correlation was analysed between FA、NAA、CST and NS function.All data showed with xs. P<0.05 as significant difference.Results:(1) The FA at infarction was decreased in all patient.lt has positive correlation with BI and negative correlation with NIHSS.This suggest CST broke more,NS function recovery less. There was a significant decrease on FA in braintem in braintem than the contralateral,which suggest WD developed in braintem. The ADC at infarction is statistically significant than the contralateral. The ADC at cerebral peduncle is not statistically significant than the contralateral.(2) The NAA at infarction was decreased to different extent than the contralateral in all patient.NAA:The lesions side with the contralateral part comparison, P<0.01;Cr、Cho: The lesions side with the contralateral part comparison, P>0.05; The NAA did not change in first week but deceasesed in first month.This suggest wallerian degeneration developed in cerebral peduncle.(3)While CST was close to infarction,the function can recovery to normal;part of CST cross from infarction,the patient may has mild to moderate dysfunction;all CST cross from infarction,the patient may has moderate to severe dysfunction.Conclusion:According to the change of ADC、FA、MRS, the severity of condition can be reflected、WD be detected early、the progressive be judge and the recovery be suggested.

Related Dissertations

  1. Comparison of the Curative Effect of Acupuncture Combined with Chinese Herb by Humid Wet Compressing and Chnese Herb by Humid Wet Compressing Solely in Treating Facia Neuritis,R277.7
  2. Observation on the Cinical Effect of Facial Neuritis Treated with Yuan-Luo point Combination plus Conventional Acupuncture.,R246
  3. Observation on the Clinical Effect of Facial Neuritis Treated with Brook-Sea Point Combination Plus Conventional Acupuncture.,R246
  4. By Stages Acupuncture Law Treatment Strok Hemiparalysis’s Clinical Research,R246
  5. A Clinical Research on Head Acupoints with Distance Along Channel Acupoints Treatment of Netrogena Tinnitus and Deafness,R246
  6. Photoacoustic Signals Analysis and Its Medical Applications Based on Focused Scanning Photoacoustic Imaging,R318.51
  7. Diffusion Tensor Imaging Study of Idiopathic Epilepsy at 3.0T High Field Magnetic Resonance Scaner,R445.2
  8. A Clinical Observation on Treating Simple Obesity by Electro-acupuncture,R246.1
  9. Effect of Acupuncture and Minimally Invasive Hematoma Aspiration on Rabbit Brain Damnification in Acute Stage of Intracerebral Hemorrhage,R245
  10. The Application Value of Magnetic Resonance Diffusion Tensor Imaging in Skeletal Muscle Tumor,R445.2
  11. 3 T Magnetic Resonance Diffusion Tensor Imaging and Fiber Tracking in Detecting Acute Spinal Cord Injury,R651.2
  12. Application of Functional MR Imaging in Diagnose for Prostate Cancer,R737.25
  13. A Study of the Expression of MMP-1 and TIMP-1 at the Enthesiopathy and the Intervention Effects by Acupuncture,R87
  14. The Application Values of 3.0T MR Perfusion Weighted Imaging and Diffusion Tensor Imaging in Grading of Cerebral Gliomas,R445.2
  15. Effects Induced by Vagus Nerve Stimulation and Electroacupuncture on Cognition and Locomotion of Rats Subjected to Ischemia-Reperfusion,R245
  16. Acupuncture geotextile vertical permeability theory,TS176.5
  17. Brain Connectivity Pattern Analysis Based on DTI,R445.2
  18. Multi-Class Pattern Analysis on Human Brain MRI Dataset,TP391.41
  19. Comparative Study of DTI with DTT and NIHSS Scoring System in Acute Ischemic Cerebral Infarction’s Prognosis Evaluation,R743.3
  20. Diffusion Tensor Imaging Using 3.0T MR Scanner in Rat C6 Glioma Model and the Correlative Study of FA Value in Infiltrated Peritumoral Edema Tissue and AQP1,R739.4

CLC: > Medicine, health > Clinical > Diagnostics > Diagnostic Imaging > Magnetic resonance imaging
© 2012 www.DissertationTopic.Net  Mobile