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A Study of Femoral Elasticity in Type 2 Diabetes by E-tracking Technique

Author: WangJunFang
Tutor: LuoLiangPing；XuHongGui
School: Jinan University
Course: Medical Imaging and Nuclear Medicine
Keywords: E-tracking Femoral arteries Elasticity Diabetes mellitus
CLC: R445.1
Type: Master's thesis
Year: 2009
Downloads: 109
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Abstract


Objective:To detect the femoral elasticity in type 2 diabetes mellitus(DM) by E-tracking(ET) technique and explore the value of ET technique in elevation the early atherosclerosis.Methods:The stiffness parameter(β),pressure strain elasticity modulus(Ep),arterial compliance(AC),argumentation index(AI) and one-point pulse wave velocity(PWVβ) of femoral arteries in 26 cases DM patients and 17 cases health adults were calculated automatically by ET technique.The diabetic patients were divided into proteinuria group(10 cases) and non-proteinuria group(16cases).The parameters of each group were analyzed using SPSS 13.0 statistic software.Results:1.Compared with the health adult,DM patients and the non-proteinuria group was different in Ep、β、AC、PWVβ(p＜0.05) expect AI(p＞0.05).The data was increased with Ep、β、PWVβin DM patients and the non-proteinuria group,while decreased with AC in DM patients and the non-proteinuria group.2.Compared with the non-proteinuria group,the data was increased with Ep、β、PWVβin proteinuria group,while decreased with AC in proteinuria group. The results showed that there were no statistical differences(p＞0.05) in the femora elasticity indexes AI between two groups.3.AC and diastolic pressure played an important role in DM patients by discriminant analysis,whose sensitivity of diagnosis on femoral elasticity in DM patients is 92.3%,and specificity is 100%.4.There were close correlations between Ep、PWVβ、βand AC(p＜0.01).Conclusion:1.E-tracking may provide an accurate and feasible method to detect the femoral elasticity in type 2 diabetes mellitus.In the femoral elasticity indexes,in contrast to the health adult,we find that Ep、β、PWV、are increasing,but AC is decreasing in DM patients.2. Compared with the non-proteinuria group,the data is increased with Ep、β、PWVβin proteinuria group,while decreased with AC in proteinuria group.The proteinuria may predict that the elasticity of arteries is damaged severly.3.The elasticity of arteries has been damaged in DM patients who have no proteinuria.4.AC and diastolic pressure play an important role in DM patients by discriminant analysis.The femoral elasticity in DM patients can be evaluated by the parameter AC sensitively.5.There are some correlations between the parameters according our research.6.The e-tracking technique shows the changes of vessel internal diameter during systolic and diastolic phase,and calculates Ep,β,PWVβ,AI and AC automaticly,which decreases error caused by human factor and makes the results accurate.The e-tracking technique can provide an important method on evaluating objectively the femoral elasticity of DM patients, on directing clinic to interrupt therapeutic measure and on showing the treating effects,the method will play a significant role in clinic.

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CLC: > Medicine, health > Clinical > Diagnostics > Diagnostic Imaging > Ultrasonic diagnosis
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