Dissertation > Excellent graduate degree dissertation topics show

The Results of Endoscopic Variceal Ligation of Esophageal Varices and the Effect on Haemodynamics of Portal Systom

Author: YuMingFang
Tutor: LiuLiNa
School: Dalian Medical University
Course: Internal Medicine
Keywords: cirrhosis endoscopic variceal ligation haemodynamics of portal system glucagon
CLC: R575.2
Type: Master's thesis
Year: 2011
Downloads: 4
Quote: 0
Read: Download Dissertation


Objective:To evaluate the efficacy of endoscopic variceal ligation(EVL) for the treatment of esophageal varices and to observe the haemodynamical changes of portal system before and after the treatment.Methods:26 patients with liver cirrhosis and esophageal varices were treated by endoscopic variceal ligation.(1)To observe the efficiency of EVL including the rate of immediate hemostasis,the rate of bleeding recrudescence and the changes of esophageal variceal.(2)To measure the dynamical changes of portal vein and its branch veins before and after EVL including the inside diameter and blood flow velocity of portal vein,spleen vein,and left gastric vein.(3)To measure the plasma level of glucagon by the method of radioimmunoassay before and after EVL.Results:(1) The successful immediate hemostasis rate of variceal ligation was 93.75%.14-20 days latter,the eradicated and diminished rate of esophageal varices was 88.46%.During 6 months there are 3 ptients bleeding again,and the rebleeding rate was 11.54%.(2) Portal vein and spleen vein in 26 patients were detected befor and after endoscopic treatmen(100%),The inside diameter of portal vein and spleen vein had no significant changes(portal vein:13.33±1.74mm vs 13.41±1.50mm.P>0.05;spleen vein:10.57±2.97 vs 10.64±2.85 , P>0.05) , but their blood flow velocity increased significantly (potal vein:24.5±4.35 cm/s vs 27.44±6.54cm/s,P<0.05;spleen vein:28.6±5.65cm/s vs 31.47±7.21cm/s,P<0.05).Left gastic vein was discovered in 24 patients(88.5%).The inside diameter and blood flow velocity of left gastric vein had no significant changes.But the blood flow direction had significant change after EVL.20 patients(87%) showed hepatofugal flow,2 patients(8.7%)bi-directional flow,and 1 patient(4.3%)hepatopetal flow before the treatment,while 15 patients(65.2%)showed hepatopetal flow,5 patients(20%) showed hepatofugal flow,and 3 patients(13.0%) bi-directional flow after treatment(P<0.01).(3) The plasma level of glucagon had no significant change before and after EVL(195.71±50.9ng/L vs 218.7±79.6ng/L, P<0.05).Conclusions:(1)Endoscopic variceal ligation is an effective method to prevent and treat esophageal variceal bleeding.(2)The dynamical measurement indicates that endoscopic variceal ligation could increase the blood flow velocity of portal vein,spleen vein and change the direction of left gastric vein.(3) The plasma level of glucagon has no obscure change before and after endoscopic variceal ligation.

Related Dissertations

  1. The Relationship between Plasma B-type Natriuretic Peptide and Liver Function in Patients with Cirrhosis,R575.2
  2. Clinical Research of Autologous Bone Marrow Stem Cell Transplantation on Liver Cirrhosis Induced by Hepatitis B,R575.2
  3. Retrospective Analysis of Infectious Precipitating Factors in Cirrhosis with Hepatic Encephalopathy,R575.2
  4. The Curative Effects of 72-week Entecavir Therapy for Patients with Decompensated Hepatitis B Virus-Related Cirrhosis,R512.62
  5. Relationship and Significance of Gene Transcription Profiles in Rat Liver Regeneration and Liver Cirrhosis Occurrence,R575.2
  6. Preliminary Investigation of Research Intestinal Microflora in Patients with Hepatic Cirrhosis by FISH and LCSM,R575.2
  7. The Value of MELD Score and Serum Total Cholesterol in Predicting the Prognsis of Patients with Decompensated Liver Cirrhosis Caused by Hepatitis B Virus,R575.2
  8. Serum Cholinesterase, Platelet, Liver Fibrosis HBV Infection in Various Stages of Clinical Significance,R575.2
  9. Clinical Research of Autologous Bone Marrow Stem Cell Transplantation for Treatment of Decompensated in Cirrhosis,R575.2
  10. The Discussion of the Relationship between Plasma B-type Natriuretic Peptide and Ascites , Output of Urine Potassium and Natrium in Patients with Cirrhosis,R575.2
  11. Clinical Study on Decompensation in Liver Cirrhosis and Establishment of Relevant Network Database,R575.2
  12. Clinical Research of Autologous Transplantation of Bone Marrow Stem Cells on Decompensate Cirrhosis Patients,R575.2
  13. Analysis of the Risk Factors Influencing the Morbidity and the Prognosis of Hepatic Encephalopathy,R747.9
  14. The Protective Effects of Glucagon-like Peptide -2 on Intestinal Barrier Function of Doxorubicin Chemotherapy in Rats,R730.5
  15. PSE lamivudine hepatitis B cirrhosis and portal hypertension clinical observation,R575.2
  16. Helicobacter pylori infection on common complication of cirrhosis risk of,R575.2
  17. Patients with decompensated cirrhosis clinical features of gallstone,R575.2
  18. Quantitation Detection of Hepatitis B Surface Antigen and Its Significance in Patients with Hepatic Cirrhosis,R575.2
  19. Clinical Significance of Hepatitis B Virus Core Gene PCR-RFLP Patterns on the Course of Hepatocellular Carcinoma and Liver Cirrhosis in China.,R735.7;R575.2
  20. Are the Surgical Indications of Barcelona Clinic Liver Cancer Staging Classification Justified? Results and Revision Proposals,R735.7

CLC: > Medicine, health > Internal Medicine > Digestive and abdominal diseases > Liver and gall bladder disease > Cirrhosis
© 2012 www.DissertationTopic.Net  Mobile