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Laparoscopy Combine with GnRH-a in the Treatment of Endometriosis Cyst

Author: ShangMinJie
Tutor: WangChangZhi
School: Dalian Medical University
Course: Obstetrics and Gynaecology
Keywords: ovarian endometriosis cyst Laparoscopy+ GnRH-a
CLC: R713
Type: Master's thesis
Year: 2011
Downloads: 11
Quote: 0
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Abstract


Objective: Recently, laparoscopy and GnRH-a are widely used in the treatment of ovarian endometriosis cyst. Both of the methods are more effective and popular than others. However, report on laparoscopy combine with GnRH-a to deal with the disease is rare. This research, which focuses on the advantage and foreground of the unite way, compares and analys the effect of Laparoscopy, GnRH-a, and Laparoscopy+ GnRH-a, and discusses the value of Laparoscopy+ GnRH-a to deal with the ovarian endometriosis cyst.Method: Look back and analyze the patients with ovarian endometriosis cyst in the second affiliated hospital from2006.7.1-2008.6.30. 52 patients were randomly choiced and divided into A, B and C group. The 25 patients treated by Laparoscopy were named A group. The 16 patients treated by Laparoscopy+ GnRH-a were named B group. The 11 patients treated by GnRH-a were named C group. Group A, B and C were compared in the relief rate of dysmenorrhea symptom, the relief rate of chronic pelvic pain, and recurrence rate after treatment. These groups were compared in curing time, treatment costs, the shortest relapse time and the menstruation after therapy.Result: Both A and B groups were operated by laparoscopy. All the operations were completed successfully, no bleeding, no laparotomy. Patients recoveried quickly, and they had no high fever, and no internal hemorrhage. All the Pathology results were that endometriosis had changed. Both B and C groups were using of injecting 3.75mg of tryptorelin. B group usage: injected 3.75 mg in the first day of first period after Laparoscopy, and later once every 28 days, a total of 4 times. C group usage: injected 3.75 mg in the first day of period, once every 28 days, a total of 6 times. All the patients of B and C groups had no menopausal symptoms and no increase of ovarian endometriosis cyst. The most expensive treatment of the three groups is B group. But the most effective treatment of the three groups is B group. There is no statistics difference in the relief rate of dysmenorrhea symptom, the relief rate of chronic pelvic pain, and menstruation. The results of follow-up after treatment and revisit after 24 month’treatment prove that laparoscopy+ GnRH-a can extend the relapse time and reduce the relapse rate.Conclusion: In recent effect, comparing with Laparoscopy + GnRH-a and single therapy to deal with ovarian endometriosis cyst, there is no significant difference. In the aspect of relapse, however, the unit method is the best one.

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CLC: > Medicine, health > Obstetrics and Gynaecology > Gynecological surgery
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