Dissertation > Excellent graduate degree dissertation topics show

Traumatic Brain Injury Patients with Cerebrospinal Fluid Myelin Basic Protein Content and Clinical Significance

Author: JiaZhiJun
Tutor: YangXiaoMing
School: Shanxi Medical
Course: Emergency Medicine
Keywords: Traumatic brain injury Myelin basic protein Cerebrospinal fluid ELISA.
CLC: R651.15
Type: Master's thesis
Year: 2009
Downloads: 57
Quote: 0
Read: Download Dissertation

Abstract


Objective: To study in patients with head injury cerebrospinal fluid myelin basic protein (MBP) levels , and to explore its clinical value for the evaluation of the condition and prognosis of patients with traumatic brain injury . Methods : by enzyme-linked immunosorbent assay (ELISA) in 40 patients with traumatic brain injury patients (GCS score 9-15 points) [ light and medium , heavy (GCS score 3-8 ) of the 20 cases of post-traumatic 1,3 seven days in CSF MBP levels in another 15 cases over the same period in the hospital intends spinal anesthesia in surgery patients with non - nervous system for the control group . Statistical methods using a repeated measures analysis of variance . Results: 1 head injury group and the control group in cerebrospinal fluid MBP level was significantly higher , the difference was significant P <0.01 ; higher than the light and medium group and severe group , the difference was statistically significant P <0.01. 2, the head injury group cerebrospinal fluid MBP level with GCS, GOS showed a significant negative correlation ( P <0.01 ) . Conclusion: myelin basic protein (MBP) is a high sensitivity and specificity of nerve cell damage markers . CSF MBP level is closely related to the head injury severity and prognosis in patients with traumatic brain injury in MBP levels in the cerebrospinal fluid can be used as important biochemical indicators to determine the condition and prognosis of patients with brain injury .

Related Dissertations

  1. Research of the Correlation About the Expression of Mfap4 in Liver Fibrosis Tissues and Concentrations of Mfap4 in Peripheral Blood Associated with Liver Pathological Grade,R575.2
  2. Establishment of ELISA for Detecting Cd-MT of Pteria Penguin and Preliminary Study of ELISA-kit,X835
  3. Establishment of Inderect ELISA for Detection of Antibodies Angainst STLV-1 and Preparation of Hybridoma Cell of Monoclonal Antibodies,R373
  4. Studies on Dynamic Regularity of Antibody Against G. Anatis and Development of Hybridoma Cell Lines Secreting Monoclonal Antibodies Against G. Anatis Lps,S858.32
  5. Purification of Human Respiratory Syncytial Virus Fusion Protein with Immunomagnetic Microsphere Technology,R373
  6. Development of Hybridoma Cell Lines Secreting Monoclonal Antibodies Against Lps Antigen of B. Melitensis,R392
  7. Construction and Application of the Integrated Gene Containing Multi-Mimotopes and VP2 of Infectious Bursal Disease Virus,S852.65
  8. The Expression of CPV-2 VP2 Gene in SF9 and Development of Indirect Elisa for Serum Antibodys,S852.65
  9. Roles of MMP-7 and Lysozyme in the Pathogenesis of Ulcerative Colitis Induced by DSS in Balb/c Mice,S858.91
  10. Epidemiologic Studies on Duck Circovirus Infection in East China and Development of Monoclonal Antibody Against Duck Circovirus,S858.32
  11. Establishment of ELISA Based on Recombinant Protein NS1 of Swine Influenza Virus and Nuclear Localization of SIV NS and NP Proteins,S858.28
  12. The Establishment of the Diagnostic Method for Detecting Antibody Against Avian Leukosis Virus Subgroup J and Function Analysis of the Long Terminal Repeat,S858.31
  13. The Expression of Rabbit Bordetella Bronchiseptica PRN Protein and the Study on Its Immunoprotection,S855.12
  14. Cloning and Expression of Fimn Gene of Bordetella Bronchiseptica in Rabbitry and Establishment of Rapid Detection Method,S858.291
  15. The Dynamical Evaluation of Three Methods to Diagnose Mycoplasma Pneumoniae Infection in Children,R725.6
  16. Expression and Antibody Preparation of sglt1 from Cyprinus CarpioL.,S917.4
  17. The Expression Mechanism of Calmodulin in Rat with Brain Contusion,R651.1
  18. H1N1 influenza virus (2009) HA protein in prokaryotic expression and ELISA Detection,R392.1
  19. Adiponectin gene signal peptide region prokaryotic expression and ELISA detection method,R392.1
  20. Domestic isoflurane inhalation anesthesia effect depends on learning and memory in adult rats related research,R965
  21. Brain myocarditis virus VP1 fragment gene of stability of the , prokaryotic expression and the Applied Research,S852.65

CLC: > Medicine, health > Surgery > Of surgery > Head and Neurosurgery > Brain > Traumatic brain injury
© 2012 www.DissertationTopic.Net  Mobile