|
Objective: To study Lymphoscintigraphy in sentinel lymph nodes (sentinel lymph node, SLN) positioned in the clinical application . Materials and Methods : from May 2006 to November 2008 79 routine sentinel lymph node biopsy (sentinel lymph node biopsy, SLNB) treated breast cancer patients Breast Surgery , Affiliated Tumor Hospital of Guangxi Medical Applications 99m Tc - dextran ( 99m Tc-DX) Lymphoscintigraphy looking SLN. Methods: Preoperative 14 ~~ 16h subcutaneous tumor surface around the tumor , the tumor under the areola injection such as 99m Tc - DX37 to 74MBq ( 1 2mci ) , breast lymphoscintigraphy , according to radioactive determine the location of the SLN radionuclide uptake , and make a mark on the skin , surgery on the body surface mark with gamma detector method with blue dye method to identify SLN sent for pathological examination . Results : (1) 99m Tc - DX SLN detection rate was 88.6% , the false negative rate was 13.6% ; the blue staining SLN detection rate , false negative rate of 86.4% , 9.1 %; combined method of SLN detection rate , false negative rate were 94.9% and 4.5%. Joint use of a higher detection rate and lower false negative rate the radionuclide law and blue staining compared with the with radionuclide method or the dye method . ( 2 ) in patients with axillary lymph node , age, tumor size , lesion location , histological type , preoperative tumor whether excisional biopsy , the tumor side do has nothing to do with the SLN identification success rate (all P gt ; 0.05) . Conclusions : (1 ) 99m < / sup > Tc -DX of SLN imaging surface positioning can accurately display the SLN location, number and lymphatic drainage can be used to locate and biopsy surgery of the breast SLNγ guidance intraoperative detection ; ( 2) The joint use of the radionuclide method and dye method has a higher detection rate compared to the with radionuclide method or the dye method ; ( 3) in patients with axillary lymph node , age, tumor size , lesion location , histological type , preoperative tumor whether excisional biopsy , tumor side are not has nothing to do with the SLN identification success rate ( P gt; 0.05 ) ; ( 4 ) SLN imaging can predict axillary lymph node status .
|