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Advances in Research on Chondroblastoma of Bone

Author: PangJuTao
Tutor: ZuoWenHai
School: Hebei Medical University
Course: Surgery
Keywords: Chondroblastoma Treatment Relapse Shift
CLC: R738
Type: Master's thesis
Year: 2009
Downloads: 38
Quote: 0
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Abstract


Chondroblastoma is a rare bone tumor , accounting for about 1% of all bone tumors , 3% of benign bone tumors . 1931 Codman described a proximal humeral epiphyseal cartilage giant cell tumor . Subsequently , Jaffe and Lichtenstein defined cell tumors as benign chondroblastoma to describe a rare multiple tumors in the epiphysis of long bones , so that the difference between the giant cell tumor . It occurs mainly in young people , and is more common in men . Chondroblastoma predilection sites including the proximal humerus , proximal femur , distal femur and proximal tibia , but other parts of the ( skull , spine , tarsal bones , etc. ) are found . Clinically , patients showed a gradual increase in pain and local tenderness , followed by swelling and limited joint mobility . X line , which showed a thin hardened edge oval lesions located in the epiphysis or bone protrusion was central or eccentric . CT manifestations , and periosteal reaction and cortical destruction performance . MR T1WI on to the main low signal on T2WI was mixed signal . Histologically , it showed benign nucleus chondroblastoma , multinucleated giant cells , and chondroblastoma mesh around the calcified structure , the so-called \The chondroblastoma not standard treatment . Treatment methods are simple intralesional curettage , cryosurgery curettage of bone graft or filled with bone cement , or auxiliary . Marginal resection and radiofrequency ablation as the selection . Chemotherapy can not be used in the treatment of cancer , radiotherapy for malignant transformation . The recurrence rate is relatively high (10% -35%) , the transfer has been reported , but is rare . The invasion risk factors Chondroblastoma not clearly identified . Primary malignant bone cartilage neuroblastoma has been reported .

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