Dissertation > Excellent graduate degree dissertation topics show

Risk Factor Analysis in Leukoaraiosis Patients with Cerebral Infarction

Author: ChenBenZuo
Tutor: LinYongZhong
School: Dalian Medical University
Course: Neurology
Keywords: Leukoaraiosis Cerebral Infarction Risk Factor
CLC: R743.3
Type: Master's thesis
Year: 2011
Downloads: 2
Quote: 0
Read: Download Dissertation

Abstract


Objective: To analyze the related risk factors in patients of cerebral infarction with leukoaraiosis and to investigate their pathogenesis.Methods: The clinical data of 221 patients with cerebral infarction underwent by MRI scans ,who were hospitalized in Department of Neurology of The Second Affiliated Hospital of Dalian Medical University from July 2010 to December 2010 with cerebral infarction were analyzed retrospectively. And they were divided into a cerebral infarction with LA group (n=156) and a cerebral infarction without LA group (n=65). A singl factor and Logistic regression analysis were performed among age, sex, smoking, alcohol consumption, hypertension, coronary heart disease, diabetes, cerebral type, high cholesterol.Results:1. The incidence of LA was 70.6% in 221 cerebral infarction patients.2. The results of single logistic regression.(1) Patients ranged in age from 21 to 93 years with a mean of 68±11 years.The 221 patients with cerebral infarction were divided into four age groups.It showed that the LA incidence in patients rose with the increasing of age(P<0.01).(2) The 221 patients were divided into a group with lacunar infarction (n=152) and a group not with lacunar infarction (n=69) according to the size of cerebral infarction .The incidence of LA in two groups was 76.3%(116/152) and 58%(40/69) respectively. And the difference was significant. The incidence of LA in patients with lacunar infarction in basal ganglia was 79.8%, when compared to other groups, the difference was significant.(3) The incidence of LA was 74.8% and 61.4% in patients with hypertension and that with normal blood pressure. The difference between the two groups was significant.(4) There was no significant difference between the group with LA and the group not with LA among sex, diabetes mellitus, hyperlipemia, arteriosclerosis, coronary heart disease, smoking and drinking.3. The age and lacunar infarction were included in the logistic regression analysis model, and the result suggested that the older were more easy to occur LA, while the incidence of LA in patients with lacunar infarction was higher than those not with infarction.Conclusion:1. The incidence of LA in cerebral infarction patients was associated with age, hypertension and lacunar infarction. But according to Logistic regression analysis ,only age and lacunar infarction was associated with the incidence of LA while adjusted the other factors.2. Small cerebral-vessel is probably the main pathophysiological basis of patients with LA . The further study of pathogenesis of LA may be helpful for us to prevent and cure it.

Related Dissertations

  1. Preliminary Studies on Peptidomics and Metabonomics of Cerebral Infarction with Blood Stasis Syndrome,R277.7
  2. Analysis of Influencing Factors of Post-endoscopic Retrograde Cholangiopancreatography Pancreatitis,R576
  3. Epidemiology of Helicobacter Pylori Infection and Associated Factors among Workers in Dalian Port Group,R181.3
  4. Stroke Risk Predicti after Transient Ischemic Attack with ABCD2+MES Score,R743.3
  5. Analysis of the Risk Factors Influencing the Morbidity and the Prognosis of Hepatic Encephalopathy,R747.9
  6. The Relationship of Serum Adiponectin、Nitric Oxide Synthase and Carotid Atherosclerosis in Patients with Acute Cerebral Infarction,R743.33
  7. The Clinical Study on Relationship between Plasma Homocysteine Levels and Recurrent Cerebral Infarction,R743.3
  8. The Effect of Berberine Hydrochloride on the Levels of Serum CRP and Complement C3, C4 in Patients with Acute Cerebral Infarction,R743.3
  9. Clinical Research on Cognitive Event-related Potential N300 in Acute Cerebral Infarction,R749.1
  10. Berberine on serum levels of superoxide dismutase and malondialdehyde levels in,R743.33
  11. Study of Image Lesion Patterns and Collateral Compensation to Cerebral Infarction Patients with the System of Ipsilateral Internal Carotid Artery Stenosis or Occlusion,R743.3
  12. Clinical Analyses of 148 Cases of Cerebral Infarction in Young Adults,R743.3
  13. The Study of Patients of Acinetobacter Baumannii Colonized Epidemic Characteristics and Risk Factors in a Surgical ICU,R181.3
  14. Massive Video Information Management System Risk Management,F426.6
  15. Comparative Study of DTI with DTT and NIHSS Scoring System in Acute Ischemic Cerebral Infarction’s Prognosis Evaluation,R743.3
  16. Clinical Analysis of Outcomes for Cervical Lymph Node Metastasis of Stage ⅠB-ⅡB Squamous Cancer of the Cervix after Surgery,R737.33
  17. Study on the Association between CETP Gene Polymorphism and Cerebral Infarction of Han Population in Hunan Province,R743.33
  18. Influence of Mild Hypothermia Treatment on Serum tPA/PAI-1 Activity in Patients with Acute Massive Cerebral Infarction,R743.3
  19. The prospective study of risk factors for disease of the heart and brain together and gathered,R743
  20. Study of 3.0T 3D-TOF MRA in Distribution of Intracranial Artery Stenosis in Patients with Cerebral Infarction,R743.3

CLC: > Medicine, health > Neurology and psychiatry > Neurology > Cerebrovascular disease > Acute cerebrovascular disease ( stroke)
© 2012 www.DissertationTopic.Net  Mobile