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The Clinical Research of YiqiJianpiHuatan Prevention and Treatment on Diabetic Patients with Coronary Heart Disease with Angina

Author: LiZhenQin
Tutor: WanXiaoGang
School: Guangzhou University of Traditional Chinese Medicine
Course: Clinical basis for TCM
Keywords: Diabetic patients with angina pectoris Spleen Qi and phlegm Prevention and cure Clinical Research
CLC: R259
Type: Master's thesis
Year: 2009
Downloads: 85
Quote: 0
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Abstract


The diabetic heart disease research purposes for severe chronic complications of diabetes, approximately 80% of patients with diabetes die of cardiovascular disease. The impact of diabetes on the heart, its pathogenesis and influencing factors of modern medicine have a certain understanding, their research has been deep into the molecular genetic level is still no exact effective indicators for early diagnosis of diabetic heart disease glycemic control, treatment, western medicine has the exact effect of the disease prevention and relief of symptoms with little success. In Medical Treatment of diabetic heart disease has made some progress, good clinical efficacy, and Chinese medicine for the prevention and treatment of the disease have certain advantages. The forward-looking survey research methods, according to the diagnostic criteria for diabetes and angina pectoris, diabetes and angina pectoris patients hospitalized July 2008 to March 2009 at the Guangzhou University of Traditional Chinese Medicine, based on the inclusion criteria and exclusion standard to choose the qualified cases 52 cases. The experimental group and the control group, while no difference given routine western medicine, including diabetes education, medication to control blood sugar, blood pressure, lipid control diet, insulin injections and oral medication, and strict control of blood glucose, fasting blood sugar control in the 4.0-7.0mmol / L, 2h postprandial blood glucose control in the 4.0-10.0mmol / L, while oral isosorbide the pears fat Sustained Release Tablets 40mg qd angina attack sublingual sublingual nitroglycerin tablets 0.5mg (record usage). The treatment group taking the Jianpiyiqi Huatan Drugs; establishment of a database, application SPSS16.0 statistical software of the treatment group and the control group data analysis, summarized contacts between. Results in 52 cases of diabetes and angina patients, two groups of Chinese medicine individual symptoms compared treatment group efficiency between 68.4% -95.7%, with an average effective rate of 88.0%; effective rate was 44.1% in the control group of symptoms, between the two groups were statistically different (P <0.05). Treatment group were treated for the Qi Jian temper phlegm law intended Recipe (Sugar Heart No. 1 party) and the control group can be effective to reduce fasting blood glucose, 2-hour postprandial blood glucose and glycated serum protein, treatment and control groups in before treatment and after treatment compared differences (* P <0.01, ** P <0.05); compared the control group and the treatment group after treatment, FPG, 2hPG, GSP was statistically significant (P <0.05). The treatment group and the control group, CHOL, TG, HDL-L, LDL-L before treatment and after treatment there are differences (* P <0.01, ** P <0.05). TG, HDL-L in the control group and the treatment group compared (P> 0.05), no difference; CHOL, LDL-L in the control group and the treatment group compared, (△ P <0.05) difference. Two groups in angina clinical efficacy of the treatment group was significantly better than the control group, a significant difference (P <0.05). Can be seen from Table 13, the two groups in the ECG efficacy significant difference (P <0.05), the treatment group than the control group. Conclusion Integrative therapy treatment of diabetic patients with coronary heart disease angina efficacy, regulate blood lipids, reduce angina attacks better than Western conventional treatment group, play a role in the prevention and treatment of diabetes angina pectoris. With traditional Chinese medicine treatment group significantly improve the role of diabetes and angina pectoris, the results show that traditional Chinese medicine, especially the the Spleen Qi phlegm Chinese medicine in improving the symptoms of diabetes and coronary heart disease in patients with angina have a distinct advantage.

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