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Electrospinning is a polymer solution using high voltage field prepared fibers , for preparing ultrafine fiber diameter in the nanometer to micrometer level . Posed by the superfine fiber membrane has a three-dimensional porous structure , large surface area and porosity is relatively high , its structure characteristics and biological tissue extracellular matrix is very similar , so for a variety of tissue engineering scaffolds . PCL is a biodegradable synthetic polymer , and its degradation products nontoxic, biocompatible better in recent years as a biomedical material attracted widespread attention. So using polycaprolactone for tissue engineering scaffold has good application value . This paper studied the PCL electrospinning process , examines the electrospinning parameters - solution concentration , voltage, receiving distance of the fiber morphology . The results showed that fiber diameter increases with concentration ; certain voltage range of the fiber diameter increases with the voltage ; receiving the greater the distance , the smaller the fiber diameter . This will be mixed into the purified nanotubes polycaprolactone solution, were prepared by electrostatic spinning polycaprolactone - carbon composite fiber membrane . By weighing method , SEM, FTIR, XRD, DSC, tensile testing, the degradation rate test , extract method, hemolysis and coagulation its dynamic structure, thermal properties, mechanical properties , degradation and biocompatibility ( cytotoxicity and blood compatibility ) were tested characterized. The results show : the composite fiber membrane had a low density and high porosity, the fiber surface is smooth. Carbon fibers and polycaprolactone no chemical interactions or interactions between very weak , a small amount of carbon nanotubes can be dispersed to increase the crystallinity of the fiber , but will produce a large number of carbon nanotubes reduces crystallinity of the fiber aggregate . Carbon fiber filler increases the mechanical properties of membranes play a role , but also accelerate the degradation of the fibers . Composite fiber membrane has good biocompatibility and good blood compatibility , its used in tissue engineering scaffolds foundation.
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