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The Preliminary Study about the Effects of Pulsed Electromagnetic Fields on Soft Tissue Healing after Clavicle Fracture of Rabbit
Author: MaWeiDong
Tutor: YeJin
School: Hubei College of Traditional Chinese Medicine
Course: TCM orthopedics and traumatology
Keywords: Pulsed electromagnetic fields Fracture Soft tissue healing
CLC: R683
Type: Master's thesis
Year: 2009
Downloads: 51
Quote: 1
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Abstract
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Objective: With the continuous deepening of the magnetic field of biological effects of pulsed electromagnetic fields on the life body damaged tissue has been great concern. Through the establishment of animal models in wound healing and wound tissue pathological changes observed pulse electromagnetic field repair damaged tissue healing; breaking tension to the wound tissue anti evaluation of wound tissue healing quality. Finally, to explore the impact of pulsed electromagnetic fields damaged soft tissue healing mechanism, in order to provide the basis for extensive clinical application of pulsed electromagnetic fields. Methods: adult Japanese white rabbits 12 only object in the middle of the clavicle Ministry, under aseptic conditions, as the center, take about 2cm incision, followed by incision exposed collarbone. Bilateral clavicular fracture with scissors. Silk fixed clavicle stump after washing, sprinkle penicillin powder to prevent infection, sutured incision, cover the wound with a sterile dressing. Continue to give after gentamicin (GM) intramuscularly three days. After the modeling were randomly divided into a control group and the experimental group, n = 6. The two groups of animals were given a standard the particles diet, clean drinking water. Postoperative pulsed magnetic field therapy instrument pole piece placed in the experimental group wound treatment, respectively, 2 times a day, every 30 minutes; rabbit control group makes magnetic therapy and other treatment methods with experimental group. Daily observation of wound healing the standard record wound healing time, wound healing, and compare the two groups wound healing length of time. 12 were killed by air embolism into a rabbit, cut the wound tissue specimens. The right side of the wound tissue application Rally experimental determination withstand the tension of the wound tissue were compared wound tissue to withstand the pull. Histological observation, fixed in 4% formaldehyde solution left side of the wound specimens were compared wound tissue pathomorphological whether differences. Results: 1 standards observed by soft tissue healing, the experimental group wound healing time is shorter than the control group, statistically significant difference (P <0.05). Rally experimental determination of wound tissue breaking the tension, breaking the tension wound tissue of the experimental group than the control group, P <0.05 by paired t-test statistically significant. 3 experimental groups wound healing-level part of the zone of recovery, visible and orderly arranged collagen, and occasionally perivascular inflammatory cells; control group, wound healing the district organizational level is not obvious, cell degeneration, edema, showed obvious inflammatory cells. Conclusion: life forms soft tissue damage, the application of pulsed electromagnetic field therapy has a role to accelerate its healing, reduce inflammation reaction.
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CLC: > Medicine, health > Surgery > Orthopaedic Surgery ( movement system diseases,orthopedic surgery ) > Fracture,bone damage
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