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The aim of the present study was designed to observe the efficacy thick the trifoliate Sanren soup treatment of chronic functional constipation (, gas Peru and damp-heat syndrome), and to explore thick the trifoliate Sanren soup the mechanism from both theoretical and clinical research system, from clinical wish to explore more effective prevention and treatment of the disease. Methods 1.80 patients are Hubei Province Traditional Chinese Medicine Hospital digestive internal medicine outpatient cases from August 2007 to February 2009. Were randomly divided into treatment and control groups, and each group of 40 people. The treatment group was 30-year-old to 62-year-old patients, average age 42 years. The control group of 33-year-old to 65-year-old patients, with an average age of 43 years. The two groups of patients with gender, age, duration and severity of the disease, Chinese medicine syndromes total integral no significant difference between comparable (P> 0.05). Treatment group given thick trifoliate San Ren Tang, the citrate Mosapride dispersible tablet (trade name of the new network is satisfied), Bifidobacterium Lactobacillus thermophilic Streptococcus the the triple viable piece (trade name Jinshuangqi). Thick trifoliate San Ren Tang the mentor experience side (by Magnolia 10g, citrus aurantium 10g, Atractylodes 20g almonds 15g, Coix seed 18g, white Kou Yan 6g, dandelion 15g, licorice 6g), these drugs Shuijianbi a , half an hour each morning and evening meal each 200ml; new network is satisfied oral, 3 times a day, each 5mg, before meals; Jinshuangqi orally, three times a day, every 4 after meals. The control group was treated with the new network is satisfied and Jinshuangqi. Usage with the former. The two groups of patients are surrounded by a treatment the security observation (project general physical examination, blood, urine, dung three routine examination; liver and kidney function; ECG; possible adverse reaction) and efficacy observed (symptoms and signs clinical total score changes before and after treatment). 3. Statistical analysis methods: data application SPSS13.0 statistical software for analysis. The ranked data Ridit inspection, counting χ ~ 2 test, measurement data using t-test. 1 total score of clinical symptoms in two groups of patients after treatment than before treatment have a significant difference (P <0.05), and the treatment group than the control group (P <0.05) TCM symptom score improvement. The treatment group of 40 cases, six cases cured, 22 cases markedly effective in 6 cases, 6 cases, the total efficiency of 85.00%. The control group of 40 patients, 2 cases were cured, 15 cases markedly effective in 7 cases, 16 cases ineffective, the total effective rate of 60.00%. The clinical cure rate of the treatment group, the total effective rate higher than that of the control group (P <0.05). Treatment group significantly improved dry stool, defecation interval, a long time of defecation, abdominal pain, chest fullness, depression, belching and other symptoms, and better than the control group; straining, bloating improvement and control group is quite . 4. Thick trifoliate San Ren Tang treatment of chronic functional constipation with significant improvement in clinical symptoms, no significant side effects, and moderate price advantages. Conclusion This research tips Integrative treatment of chronic functional constipation (, gas Peru and damp-heat syndrome) have good clinical efficacy, its better than Western medicine alone group. Regulating bowel movement two-way, promote the secretion of gastrointestinal function, softening the fecal matter, promote stool may have thick the trifoliate three Ren Decoction combined with western medicine disease research from the theory of modern pharmacology, synergistic enhancement . Description the thick the trifoliate three jen Decoction group party meet clinical practice, certainly has some efficacy in the treatment of functional constipation (, gas Peru and damp-heat syndrome), worthy of further research and extension.
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