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Objective: To observe the experimental group (Xiao Chai Hu Decoction estazolam alprazolam) clinical efficacy for the treatment of liver-fire type of insomnia and its Sleep Disorder Scale (Sleep Dysfunction Rating Scale, SDRS), Pittsburgh Sleep Quality Index (Pittsburgh sleep Quality Index , PSQI), side effects scale (Treatment Emergent Symptom Scale, TESS) scores affect, so as to provide clinical use the Xiaochaihu Decoction treatment of liver-fire type of insomnia, the theoretical basis. Methods: 68 patients are Wuhan Chinese and Western Medicine Hospital, the TCM medical clinic and hospital and patient. Met the inclusion criteria, 71 patients were randomly divided into experimental group (Xiao Chai Hu Decoction estazolam alprazolam), control group (estazolam). Exclude the depigmentation cases, the experimental group of 35 cases, the control group of 33 patients. One week of the 68 cases of liver-fire type of insomnia patients before treatment stop everything to improve sleep therapy, estazolam (night before going to sleep 1mg ~ 2mg) were given oral, the treatment group add services Xiaochaihu decoction decoction (firewood Hu 15g, Scutellaria 10g, Pinellia 10g, ginger 10g, Fu Shen 15g, jujube 5 licorice 6g. jianfu law: the first drug with water soak for half an hour, Tai gently boiling for half an hour then simmer , a daily, three times daily, before going to sleep clothing head fried the next morning, afternoon decoction two, three fried two weeks for a course, each successive group treated for 4 weeks to Sleep Disorders Scale ( SDRS) for reference as the evaluation standard, the experimental group was observed after 4 weeks (Xiao Chai Hu Decoction estazolam alprazolam), clinical efficacy for the treatment of liver-fire type of insomnia in the control group (estazolam); experimental group were recorded and control group, two weeks after 14 and 28 days of treatment, and withdrawal of SDRS PSQI global score, TESS score results: (1) after 4 weeks of treatment, the experimental group and the control group, significant efficiency difference was not statistically significant (P > 0.05), and total efficiency, the clinical cure rate difference was statistically significant (P <0.05), total effective rate of the experimental group, the clinical cure rates were 91.43%, 34.29%; total effective rate in the control group, clinical cure The clinically superior rate to 69.70%, and 12.12%, respectively, suggesting that small Bupleurum Decoction combined with estazolam treatment of liver-fire type of insomnia with estazolam group. (2) the experimental group and the control group of sleep disorders Scale (Sleep Dysfunct ion RatingScale, SDRS) score compared, the difference was not statistically significant (P> 0.05) before treatment in the treatment of 14 days, 28 days and after stopping two weeks the difference was statistically significant (P <0.05), prompted the clinical efficacy of the experimental group than the control group. (3) the experimental group and the control group, the Pittsburgh Sleep Quality Index (Pittsburgh SleepQuality Index, PSQI) score compared before treatment, the difference was not statistically significant (P> 0.05), in the treatment of 14 days, 28 days and after stopping two weeks the difference was statistically significant (P <0.05), prompted the clinical efficacy of the experimental group than the control group (4) the experimental group and the control group vice Response Inventory (Treatment Emergent Symptomscale, TENs) score compared, no statistically significant difference in the treatment of the first 14 days (P> 0.05), after 28 days of treatment and withdrawal two weeks the difference was statistically significant (P < 0.05), the side effects of the experimental group scores prompted Xiao Chai Hu Tang joint estazolam than fewer adverse reactions alone estazolam Conclusion: Small Bupleurum Decoction combined with estazolam therapy stagnation of fire type of insomnia have a good effect, its efficacy is superior with estazolam, and fewer side effects, further research needs to be carried out.
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