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Contrast-enhanced MRI and diffusion imaging of intracranial tumor grade oligodendrocytes preliminary study on different levels of the first part of intracranial tumors oligodendrocytes Objective To investigate the MRI findings of intracranial gliomas oligodendrocytes MRI findings, with relatively low levels High-level performance oligodendrocytes glioma MRI features and differences to explore on the tumor grade valuable indicators of MRI images. Methods A retrospective analysis of 30 cases of 31 pathologically confirmed before treatment of intracranial tumors oligodendrocytes MRI imaging findings, and pathological classification and classification for control study. Results 31 oligodendrocytes intracranial tumors, 24 for the simple type oligodendrocytes glioma (OligodendrogliomaOD), which anaplastic (Ⅲ level) 9, differentiated (Ⅱ grade) 15; 7 is mixed oligodendrocytes astrocytoma (Oligoastrocytoma OA), which Ⅲ grade 4, Ⅱ grade 3. Tumors were located in the superficial parts of the cortex of the brain substance and subcortical (29), may apply to the deep and even extends to the contralateral hemisphere (12); deep structure found in violation of more high-grade tumors (Ⅲ Ⅱ grade level on 9/13 Vs 5/18 P = 0.033); sharp edges (4/12 Vs 10/18), part of the definition (2/13 Vs 2/18), unclear (7/13 Vs 6/18). After intravenous injection of contrast agent, in order to strengthen high-level common tumors and significantly enhanced the main (Ⅲ level for grade Ⅱ, 11/13 Vs8/18, p = 0.032, degree of enhancement obviously 10/13 Vs 4/18, p = 0.004, mild 1/13 Vs 4/18); enhancement pattern (Ⅲ level right Ⅱ, ring enhancement 9/13 Vs 2/18, P = 0.002; uniform nodules or punctate enhancement 15% 2/13 Vs 33 % 6/18). Conclusion oligodendrocytes tumor grade Ⅱ and Ⅲ grade oligodendrocytes tumor size, lesion edge features such as MRI showed no significant difference on; deep structure of tumor invasion, such as ring enhancement after contrast MRI features more common in high-grade tumors . The second part of the minimum apparent diffusion coefficient of intracranial tumor grade oligodendrocytes and type the value Objective: To evaluate the minimum apparent diffusion coefficient of intracranial tumor grade oligodendrocytes and type value. Materials and Methods: 24 pathologically confirmed oligodendrocytes tumor patients (13 males and 11 females, average age 45 years), including four Ⅲ grade (anaplastic) oligodendroglioma astrocytoma (oligoastrocytomas OA), 6 Ⅲ grade (anaplastic) oligodendroglioma gliomas (oligodendrogliomas OD), 2 个 Ⅱ grade astrocytoma and oligodendroglioma 12 Ⅱ grade glioma oligodendrocytes of 4 groups. Substantial part of the tumor was measured minimum apparent diffusion coefficient (minimum apparent diffusion coefficient ADC min ) value and the contralateral normal brain ADC values ??and calculate the relative value (relative ADC min ). Comparison of different classification and pathological type group average rADC min values ??and statistical analysis. Results: The different type oligodendrocytes average tumor rADC min , respectively Ⅲ grade OA 0.95 ± 0.05, Ⅲ grade OD 1.11 ± 0.30, Ⅱ grade OA 1.69 ± 0.59, Ⅱ grade OD 1.45 ± 0.41, the degree of malignancy and tumor grade and negatively correlated (P = 0.004). rADC min in two levels oligodendrocytes tumors have significantly different (P = 0.014), further pairwise comparisons show rADC min in OA and grade Ⅱ Ⅲ grade OD, Ⅱ grade OA were significant differences between (P = 0.027, P = 0.029,)., but with grade Ⅱ Ⅲ grade OD OD, Ⅱ grade OA average rADC min no significant difference (P = 0,067 ~ 0.081); when the cutoff value rADC min = 1.03 when oligodendrocytes differentiate tumor grade Ⅱ and Ⅲ grade OA sensitivity of 100% and a specificity of 100%, but the identification of two species level oligodendrocytes tumor sensitivity is only 60% and specificity of 100%. Conclusion: rADC min oligodendrocytes can provide valuable information on tumor grade, select the optimal cut-off value rADC min = 1.03, can be identified oligodendrocytes star Ⅲ grade cell tumors and tumor grade Ⅱ oligodendrocytes; However, due to grade Ⅲ OD its rADC min and the rest of the groups overlap, alone rADC min distinguish two levels of tumor limited value, rADC min is less than 1.03 can be excluded grade Ⅱ oligodendrocytes tumors. The third part of oligodendrocytes enhanced MRI tumor and tumor grade Objective To investigate the correlation of intracranial glioma oligodendrocytes enhanced MRI performance, analysis of tumor enhancement correlation with tumor grade. Methods A retrospective analysis of 30 cases of 31 pathologically confirmed before treatment of intracranial tumors oligodendrocytes MRI image data, the degree of enhancement observed indicators including lesions, enhancement pattern, determination of tumor enhancement ratio with tumor grade and subtype as a control study. Results 31 oligodendrocytes intracranial tumors, 24 for the simple type oligodendrocytes glioma (OligodendrogliomaOD), which anaplastic (Ⅲ level) 9, differentiated (Ⅱ grade) 15; 7 is mixed oligodendrocytes astrocytoma (Oligoastrocytoma OA), which Ⅲ grade 4, Ⅱ grade 3. The mean tumor enhancement ratio (contrast enhancement ratio CER) were grade Ⅱ OD: 1.11 ± 0.11, Ⅱ grade OA: 1.37 ± 0.31, Ⅲ grade OD: 1.65 ± 0.18, Ⅲ grade OA: 2.16 ± 0.32, and tumor grade and degree of malignancy There was a positive correlation (P = 0.000), in both grade tumors have significantly different (p = 0.002). When the cut-off value CER = 1.30 when determining tumor sensitivity level of 85%, specificity 78%. Three kinds of enhancement seen in 19 with enhanced tumor (Ⅲ level for grade Ⅱ were 11/13 Vs 8/18): uniform punctate nodular enhancement (7/13 Vs 7/18), ring enhancement (9 / 13 Vs 2/18), large enhancement (2/13 Vs 0). Conclusion MRI is more common in high-grade tumors enhanced oligodendrocyte tumors, the mean tumor enhancement ratio according to grade Ⅱ OD, Ⅱ grade OA, Ⅲ grade OD, Ⅲ grade upward trend in the order of OA. Punctate, nodular enhancement is characteristic of the tumor enhancement pattern, one ring enhancement tumor indicates the emergence of high-level possible.
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