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Study of Acute Stroke Registry in Stroke Unit and Analysis of Related Factors

Author: CaoHaiYan
Tutor: XueRong;WangJingHua;ZhangLiQun
School: Tianjin Medical University
Course: Neurology
Keywords: Stroke Register OCSP TOAST Parting Risk factors Gender Diabetes
CLC: R743.3
Type: Master's thesis
Year: 2009
Downloads: 280
Quote: 0
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Abstract


Objective stroke unit with acute stroke inpatient stroke epidemiology, risk factors, mechanisms of stroke, stroke subtypes and outcome of stroke and other useful information, registration and related factors, a better grasp of the clinical features of stroke, dangerous factors, etiology and pathogenesis of typing, and ultimately to standardize and improve the overall level of diagnosis and treatment of acute cerebrovascular disease, reduce death and disability, the purpose to improve the quality of life of patients and their families. This study collected continuously incidence of 748 cases of stroke patients within 14 days of the stroke unit. This is a registration study based on hospital admissions, and the use of a computer database system, for all patients using computer unified coding. All patients the diagnosis was confirmed by CT and MRI. This study began in December 2007 ending in February 2009. The analysis of the patient's basic information, risk factors, the incidence to the time interval of the hospital, stroke type, duration of hospitalization, during hospitalization, a variety of complications, mortality, drug treatment, discharge, gender patients divided into two groups were compared between the two groups of patients with stroke characteristics, and analysis of diabetes and clinical characteristics of patients with cerebral infarction. Results 748 stroke patients in the stroke unit cerebral infarction in 585 cases (78.21%), 98 cases (13.10%) of hemorrhagic stroke, transient cerebral ischemic attack (TIA), 65 cases (8.69%). 457 cases of male patients (61.10%) female patients, 291 cases (38.90%). Age of 65.95 ± 11.90 years of age, length of hospital stay was 16.37 ± 9.57 days. 52.81% of the patients to the hospital within 24 hours of onset, only 4.01% of the patients arrived at the hospital within two hours of the onset of treatment. Risk factor for stroke, the highest incidence of hypertension accounted for 71.39%, followed by smoking, drinking, diabetes, ratio were respectively: 47.73%, 39.30%, 35.70%. 23.93% of patients with hypertension, smoking and drinking three risk factors. Before admission for primary prevention of anti-hypertensive drugs, anti-platelet drugs, statins were lower proportion. OCSP classification in cerebral infarction, lacunar infarction (Laci) is the most common type, the proportion was 30.94%, followed by partial anterior circulation infarction (PACI) (30.60%). A cerebral infarction TOAST typing artery atherosclerosis infarction (LAA) is the most common type, accounting for 43.59%, followed by small artery occlusion (SAO) (30.94%). The TACI-most common cause of PACI type are large artery atherosclerotic artery infarction (LAA), the most common type LACI small artery occlusion (SAO). The most common site of cerebral infarction in the basal ganglia (42.23%). Cerebral hemorrhage the most common site for the basal ganglia, thalamus (66.67%). The head MRA highest testing rates in this study, 15.51%, followed by the neck vascular ultrasound (8.08%). DSA examination was only 4.01%. Patients with carotid artery stenosis or occlusion of the complex and diverse clinical manifestations, anatomic variations and individual vascular compensatory collateral circulation and the pathogenesis of infarction. The highest incidence of complications during hospitalization for urinary tract infection, the rate was 36.50%. Depression was 36.10%. Brain-heart syndrome was 65.47%. The treatment of acute stroke unit specification. Patients discharged reduce the degree of neurological deficit on admission, 59.36% of patients in the discharge mRS score ≤ 2. The hospital mortality was 3.74%. 71.43% of the patients who died, death in patients with stroke is directly related to 28.57% of the patients died indirectly related to stroke. Discharge medications proportion of the drug compared with the proportion of pre-hospital medication. The three-month follow-up mortality rate was 4.31%, significantly improve the viability of the three-month follow-up of patients compared with discharge. Three-month follow-up oral drug proportion than those of Discharge medications reduce the proportion. , 66.67% of death in patients with stroke is directly related to the death of patients. 33.33% of the patients died and indirectly related to stroke. Male and female patients: the female patients older than male patients, low level of education, the incidence to the interval to the hospital. Hospital female patients during the check made less than men, such as vascular examination, transthoracic echocardiography, and so on. Female patients than male patients on admission neurological deficit seriously improved during hospitalization rate is low, the high incidence of complications and poor prognosis. Diabetes patients with cerebral infarction compared with non-diabetic patients with risk factors for multiple high incidence of infarction and cerebral infarction compared with non-diabetic patients, severe neurological deficit, the high incidence of depression, nerve function improved discharge poor prognosis, high mortality. Conclusion The basic demographic characteristics and other parts of the world reported stroke registry findings are consistent. The present study, ischemic stroke is more common than hemorrhagic stroke, both the proportion of 86.9% and 13.10%, respectively. The most common lesion of ischemic stroke and hemorrhagic stroke are the basal ganglia, thalamus. Low public stroke the ability to identify, first aid poor awareness, pre-hospital care system is not perfect, very serious prehospital delay. Risk factor for stroke, the highest incidence of high blood pressure. Significant proportion of patients with concomitant two or three and more risk factors, stroke, multiple risk factors for the incidence of stroke. Infarction OCSP classification, the most common lacunar infarction. TOAST classification, the large artery atherosclerotic infarction (LAA) is the most common. The acute phase of OCSP classification prompt causes, useful to guide clinical treatment. Vascular screening is low in the research stage, clinicians lack of knowledge of the importance of the vascular examination, the etiology and pathogenesis of ischemic stroke diagnosis of type is not perfect. Standardized and effective treatment of acute stroke unit. Patients the cause of death, cause of death and stroke are directly related to the majority of the remaining patients the cause of death and stroke indirectly related, so concerned about the central respiratory and circulatory failure, brain herniation and severe pulmonary infections, gastrointestinal bleeding and other complications, reduce died rate. System is not perfect primary and secondary prevention of stroke. Female stroke patients than men in terms of disease, treatment, clinical diagnosis and treatment and prognosis is unique. Diabetic patients with cerebral infarction compared with non-diabetic patients with risk factors for severe neurological deficit, the high incidence of depression, nerve function improved low discharge, poor prognosis and high mortality.

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CLC: > Medicine, health > Neurology and psychiatry > Neurology > Cerebrovascular disease > Acute cerebrovascular disease ( stroke)
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