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A Study on the HBsAg Carrying Status and the Influential Factors of HBsAg Carrier among Primary School Children in Mayang County

Author: ZuoJianWan
Tutor: LiJuanSheng
School: Lanzhou University
Course: Epidemiology and Biostatistics,
Keywords: Viral hepatitis B Hepatitis B virus antigen antibody Epidemiological characteristics Pupils Influencing factors
CLC: R181.3
Type: Master's thesis
Year: 2009
Downloads: 20
Quote: 1
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Abstract


The purpose of master Ma Zhongyang County pupils HBsAg-carry status and level of immunity against hepatitis B; explore the influencing factors of Ma Zhongyang County pupils HBsAg carriers, to take effective measures to reduce the mortality and morbidity of HBsAg carrier, to provide the basis for further control hepatitis B prevalence. Method 1, using stratified random cluster sampling method is divided into two layers, according to the urban and rural units of each layer to the county's primary schools to be extracted 6 to 13-year-old school pupils surveyed using ELISA was used to detect hepatitis B HBsAg, anti-HBs, HBeAg, anti-HBe and anti-HBc. 2, according to test results, a 1:2 case-control study design, cases of HBsAg positive pupils choose their same sex, the HBsAg negative primary school students do not differ by more than 2-year-old the same villages or streets, and the age of the upper and lower control, the use of a unified The survey, conducted a questionnaire survey to obtain the relevant influencing factors. Results 1, Ma Zhongyang County pupils HBsAg positive rate of 3.04% boys and 3.74%, and 2.29% for girls, statistical tests, both male and female differences were statistically significant (P <0.01); each age group between HBsAg positive rate difference between urban and rural students were not statistically significant (P> 0.05). 2, the total anti-HBs positive rate was 44.44% boys and 43.55%, and 45.40% for girls, the difference was not statistically significant (P> 0.05), but all age groups, urban and rural students total anti-HBs The rate difference was statistically significant (P <0.005). 3, case-control study of primary school students of HBsAg carriers Impact factors: (1) single-factor statistical test, mother's education level, family income, intramuscular injection or drip, tooth extraction, vaccination, disposable syringes, one of a needle tube, the hepatitis B vaccine, the first dose of hepatitis B vaccine timely vaccination, vaccinated hepatitis B vaccine, hepatitis B vaccine booster vaccination, the mother is hepatitis B patients or HBsAg carriers factors were statistically significant; (2) multivariate conditional logistic regression analysis, mother's education level, intramuscular injection or drip, tooth extraction, timely vaccination of the first dose of hepatitis B vaccine, disposable syringes, the mother is hepatitis B patients or carriers of HBsAg as influencing factors. Conclusion 1 Ma the Zhongyang pupils HBsAg positive rate is relatively high, there is a gender difference; hepatitis B vaccination achieved significant results, and so change the distribution of hepatitis B in the county's primary school population in the urban and rural; 2, the total anti-HBs positive rate is not high, and there are still a large number of susceptible, should vigorously carry the hepatitis B vaccine in the primary school students to replant and strengthen vaccination. 3, intramuscular injection or drip, tooth extraction, the mother is hepatitis B patients or HBsAg carriers pupils HBsAg positive risk factors, the mother's education level, the first dose of hepatitis B vaccine timely immunization, disposable syringes pupils HBsAg positive protective factors.

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CLC: > Medicine, health > Preventive Medicine,Health > Epidemiology and Prevention of Disease > Epidemiology of the basic theory and methods > Special epidemiological each
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