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Objective: To understand the Dalian Medical University First Affiliated Hospital Medical Center 1309 healthy non-alcoholic fatty liver disease (nonalcoholic fatty liver disease, NAFLD) The prevalence, characteristics and major risk factors. Subjects and methods: physical examination data collected in Dalian Medical University First Affiliated Hospital Medical Center from January 2007 to May routine physical examination, complete data for a total of 1309 cases. No serious cardiovascular and cerebrovascular diseases, cancer, kidney failure and other major diseases of the selected candidates have been removed amended in February 2006, \. Male 755, female 554 cases, aged 18 to 85 years old. Type B ultrasound diagnosis of fatty liver disease (fatty liver disease, FLD), 296 cases were male and 232 cases, 64 cases of women between the ages of 18 to 77 years. More than 1013 cases of normal control group, male 523, female 490 cases. Changes in the overall prevalence of NAFLD, men and women, the prevalence of features, as well as the age of the NAFLD group and the control group, blood lipids, liver enzymology, complications and its risk factors to be assessed. Results: 1. Survey of 1309 people, 296 people of NAFLD, the overall prevalence rate of 22.62%, 30.73% prevalence rate for male and female prevalence rate was 11.55%; prevalence of men and women the difference was statistically significant (P lt ; 0.05). Gender, stratified by age, 40 to 49-year-old was sick for the overall and men peak of 29.84% and 38.33%, respectively; peak of sick women ≥ 70 years of age group, 28.57%. Before age 50, the prevalence of male than female, male and female prevalence rates were significantly different (P lt; 0.05); sick women after the age of 60 than men, but no significant difference in prevalence between men and women (P gt; 0.05) NAFLD group age, body mass index (BMI), waist circumference, blood uric acid (UA), systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting blood glucose, triglycerides (TG), cholesterol (Chol), low-density lipoprotein protein (LDL), high density lipoprotein (HDL) average than those in the control group, the difference was significant (p lt; 0.001). NAFLD group alanine aminotransferase (ALT), gamma-glutamine GGT (GGT) average than the control group, the difference was significant (P respectively lt; 0.001 lt; 0.05), and ALT with. 3.NAFLD complications, abdominal obesity prevalence rate of 93.24 percent, 51.69 percent of hypertension, hypertriglyceridemia 51.35%, 47.97% overweight, obese 43.24% (overweight and obese 91.22%), hypercholesterolemia 39.86%, diabetes (fasting blood glucose) 21.96%, 16.22% of hyperuricemia, an abnormal electrocardiogram 9.12%; liver gallstones and kidney stones prevalence rates were 3.72%, 1.69%. The NAFLD group complications prevalence compared with control group, liver gallstones, kidney stones, between the two groups was not statistically significant (P gt; 0.05), I have significant difference (P lt; 0.05), in which abdominal obesity, overweight and obesity, overweight, obesity, hypertriglyceridemia, hypertension, diabetes (including fasting blood glucose) and hyperuricemia difference is significant. 4.NAFLD risk factors: multivariate unconditional logistic regression analysis, body mass index (overweight and obesity) increases, high triglycerides, fasting blood sugar (diabetes), increased waist circumference (abdominal obesity), blood pressure elevated, high blood uric acid and NAFLD was positively correlated 0R values ??were greater than 1, an independent risk factor for NAFLD. The top three most closely related with NAFLD increased body mass index, high triglycerides, fasting blood glucose. Conclusion: The high prevalence of NAFLD in our hospital examination, higher in men than women, the total prevalence and the prevalence of men and women age, changes in the characteristics; NAFLD easily combined with obesity, hypertension, hypertriglyceridemia, high cholesterol, diabetes or fasting hyperglycemia, hyperuricemia; increasing body mass index, high triglycerides, fasting blood glucose, increased waist circumference, high blood pressure, high uric acid is an independent risk factor for NAFLD.
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