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The 1:1 Matched Case-control Analysis on the Relative Factors of Amblyopia

Author: ChangMin
Tutor: WangSuPing
School: Shanxi Medical
Course: Epidemiology
Keywords: Amblyopia Relevant factors Matched case-control study logistic regression analysis Interactions Dose - response relationship
CLC: R777.44
Type: Master's thesis
Year: 2011
Downloads: 38
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Abstract


Objective: To investigate the prevalence of amblyopia in children related factors . METHODS : A 1:1 matched case-control study of 100 cases of newly diagnosed children with amblyopia and cases of the same sex , the same area of ??residence , age, a difference of less than ± 0.5 years , 100 healthy children to investigate . The application of conditional logistic regression analysis method analysis of congenital factors , acquired visually stimulating environment, as well as child nutrition factors for amblyopia sick . Results: Univariate analysis showed that the number of pregnancies , often Habitat lighting , father of child-bearing age have access to computers , the mother during pregnancy , children the calcium and fat content of copper content of zinc in hair and plasma glutathione peroxidase low vitality of the suffering the greater the risk of amblyopia ; children sweets intake , eating vegetables , fruits , seafood , beans , the mother during pregnancy eat more fruits , seafood and beans low risk of suffering from amblyopia . Multivariate logistic regression analysis showed that the mother pregnancies , children often home environment lighting is poor intake of sweets , lower hair zinc content and plasma glutathione peroxidase activity is a major risk factor for amblyopia occurs . Eat more seafood protective factors . Interaction results show that the number of pregnancies , sweets intake was antagonistic role in the occurrence of amblyopia ; additive model support children often living environment lighting , sweets intake in the incidence of amblyopia was synergistic . Sweets intake with amblyopia occurred in a dose - response relationship . Conclusion: The prevalence of amblyopia in children affected by multiple factors , mother pregnancies , children often Habitat lighting , and more sweets intake , low hair zinc content and plasma glutathione peroxidase activity is a major risk of amblyopia factor. Eat more seafood protective factors . Number of pregnancies , sweets intake was antagonistic role in the occurrence of amblyopia ; the additive model support children often Habitat lighting , sweets intake in the incidence of amblyopia was synergy . Sweets intake with amblyopia occurred in a dose - response relationship . Tip congenital environment , acquired visually stimulating environment, and child nutrition factors influence the occurrence of amblyopia in children .

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CLC: > Medicine, health > Ophthalmology > Ocular adnexal organ disease > Ocular disease and strabismus > Amblyopia
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