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The purpose of Youth incidence of stroke in recent years has increased year by year, is increasingly becoming a major culprit endangering our national health, and the etiology and risk factors relative to the traditional elderly stroke is more complex. This article will explore the Southwest region of young people under the age of 45 ischemic stroke etiology, risk factors and stroke subtypes characteristics and cerebral angiography characteristics and to make a comparison with the existing relevant literature reports. Methods A retrospective analysis from December 2008 to October 2010 in the Affiliated Hospital of Jining Medical College, guests under the age of 45 young patients with ischemic stroke 95 cases, including 71 males, 24 females cases, all admission by CT or MRI, and all line echocardiography, blood sugar, blood lipids, blood rheology, anti-neutrophil cytoplasmic antibody, anti-cardiolipin antibodies and vascular aspects of the inspection, including transcranial Doppler, neck vascular ultrasound, part of the lines of magnetic resonance angiography (MRA) and / or further line of cerebral angiography (DSA) examination, stroke patients were classified according to TOAST classification method. Enter the statistics SPSS 17.0 computer statistical software, the establishment of a database, using t test, analysis of variance to determine whether the difference was statistically significant between variables. P lt; 0.05 was considered statistically significant. The percentage of different causes and risk factors and statistics, the percentage of each stroke subtype analysis of cerebral angiography shows the stenosis location and characteristics. Results from the Southwest region of 545 cases of ischemic stroke patients stay in the Affiliated Hospital of Jining Medical College from December 2008 to October 2010, in which young patients with ischemic stroke 95 cases, accounting for 17.4%. The patients had a mean age of onset (39.9 ± 7.11) years old, male and female incidence rate ratio of 3:1, the onset of the gender composition of the difference was statistically significant (P lt; 0.05). Smoking in all the risk factors take the first one, there were 41 cases, accounting for 43.2% of the total sample were male patients. Hypertension occupy the second place, there were 34 cases, 35.8% of the total sample, including 26 cases of male patients with hypertension, accounting for 27.4%, eight cases of female patients with hypertension, accounting for 8.4%. Alcoholism risk factors for stroke in all youth occupy third place, with 32 cases, accounting for 33.7%, and all were male. Anticardiolipin antibody levels were 7 cases, accounting for 7.4%, of which 5 cases of female patients. 7 cases of diabetes, accounting for 7.4%. Female patients, oral contraceptives in 2 cases (9.5%). Family history of stroke cases, accounting for 1.1%. Youth ischemic stroke etiology according to TOAST classification method to classify large artery atherosclerosis stroke (large artery atherosclerosis, LAA) 27 cases (28.4%), cardiogenic cerebral infarction (cardioaortic embolism, CE) 4 (4.2 %); the small arterial occlusive stroke or lacunar stroke (small artery occlusion, SAO) 8 (8.4%); other causes of ischemic stroke (stroke Determined Etiology of other SOE), 21 patients (22.1% ), moyamoya disease in 10 cases, accounting for 10.5% of the large sample. Unexplained stroke (stroke of undetermined etiology, SUE) 35 (36.8%). The top three risk factors are smoking (43.2%), hypertension (35.8%), alcohol (33.7%). Among them, the most important risk factor in the large artery atherosclerosis stroke (LAA) hypertension (55.6%), the most important risk factors in the small arterial occlusive stroke or lacunar stroke (SAO), alcohol (50.0 %), unexplained stroke (SUE) is the most important risk factors are smoking (48.6%). Cerebral angiography (DSA) moyamoya disease in 10 patients (13.3%). 30 patients with varying degrees of cerebral artery stenosis and occlusion. Simply the left internal carotid artery stenosis in 10 cases (13.3%), which simply left middle cerebral artery stenosis in 4 cases (5.3%), the left internal carotid artery stenosis in 6 patients (8.0%); right internal jugular the arterial system stenosis in 7 cases (9.3%), the right middle cerebral artery stenosis in 6 patients (8.0%), the right carotid artery stenosis in 1 case (1.3%); bilateral carotid artery system have narrow (6.7%); simple vertebrobasilar stenosis in 6 patients (8.0%), which simply left vertebral artery stenosis, the right vertebral artery stenosis 2 cases (2.7%), bilateral vertebral artery are stenosis in 3 cases (4.0%), basilar artery stenosis in 1 case (1.3%); 2 cases of internal carotid artery and vertebral basilar artery stenosis have, respectively, for the left and right internal carotid artery and vertebral basilar artery and right carotid artery and the right vertebral artery; anterior circulation stenosis (32.0%) was significantly higher than the systemic vascular stenosis (8.0%) proportion. Intracranial arterial stenosis was significantly higher than extracranial artery stenosis, intracranial arterial stenosis in 20 patients (26.7%), extracranial artery stenosis in 10 patients (13.3%). Conclusion This study found: (1) The gender composition differences: young ischemic stroke in male patients compared with the proportion of female patients by analyzing the causes and risk factors of young ischemic stroke. The ratio of the two is 3:1. (2) characteristics of risk factors: Youth stroke etiology and risk factors than the traditional age-stroke more diversity, in addition to outside the traditional sense of hypertension, diabetes, hyperlipidemia, oral contraceptives, increased anti-cardiolipin antibodies and smoking Drinking mused be taken into account. This study shows that smoking, hypertension, alcohol consumption is the young stroke of the Southwest region of the most common risk factors may and local Sean Shigeyoshi, forthright music drinking related to the culture and customs. Prompted to strengthen education to quit alcohol limit, a pricey awareness, control of blood pressure, prevention of ischemic stroke is particularly important for young people (especially men). (3) the stroke subtypes Features: proportion of unexplained stroke, 35 cases, accounting for 36.8%; followed by large-artery atherosclerosis stroke, 27 cases, accounting for 28.4%. Large artery atherosclerosis stroke higher proportion of mainly young people with early-onset atherosclerosis related. (4) risk factors and stroke subtypes: male patients aorta porridge-like the hardening stroke compared female patients, may be related to the the male patients smoking and alcoholism proportion of higher. Among them, the most important risk factor in the large artery atherosclerosis stroke (LAA) hypertension (55.6%), the most important risk factors in the small arterial occlusive stroke or lacunar stroke (SAO), alcohol (50.0 %), unexplained stroke (SUE) is the most important risk factors are smoking (48.6%). (5) Youth stroke with moyamoya disease: moyamoya disease (Moyamoya disease) in the local common, may be related to the Southwest region rivers and lakes Shuibo more, tend to have a history of exposure to contaminated water and eating local lobster, screws, etc. due to leptospirosis infection relevant. (6) DSA cerebral vascular stenosis: the group of 95 patients, 75 cases of cerebral angiography, 30 patients with varying degrees of cerebral artery stenosis and occlusion, the incidence rate of 40.0%. Vascular stenosis in the anterior circulation stenosis later common extracranial stenosis common intracranial vascular stenosis.
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