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Clinical Research on Improving Insulin Resistance of Type 2 Diabetes Patients with Shengmaijiangtang Potion

Author: WangFeiFei
Tutor: XuYunSheng
School: Shandong University of Traditional Chinese Medicine
Course: Chinese medical science
Keywords: Shengmai hypoglycemic drink Insulin resistance in type 2 diabetes Nourishing , clearing blood Clinical Research
CLC: R259
Type: Master's thesis
Year: 2011
Downloads: 59
Quote: 0
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Abstract


Objective: Through clinical research, observation and verification by nourishing, heat the blood is the principle of prescription hypoglycemic drink Shengmai type 2 diabetes insulin resistance effect, and further explore its mechanism. Methods: A randomized, controlled way, to meet the inclusion criteria, 60 patients with type 2 diabetes were divided into treatment group (30 cases) and control group (30 cases). In the conventional basic therapy, while the treatment group took Shengmai hypoglycemic drink, the control group took metformin hydrochloride enteric-coated tablets, two groups were continuous medication eight weeks as a course. TCM symptoms and signs before and after treatment, body mass index (BMI), fasting plasma glucose (FPG), 2-hour postprandial glucose (2hPG), glycosylated hemoglobin (HbA1C), fasting insulin (FINS), insulin resistance index (IRI), insulin sensitivity index (IAI), lipids (TC, TG, LDL-C, HDL-C), blood rheology changes in each index. Results: 1. Patients treated with TCM symptoms and signs were significantly improved compared with the control group, there were significant differences (P lt; 0.05 or P lt; 0.01); 2. TCM treatment group was significantly lower total score of symptoms and signs, compared with before treatment there was a significant difference (P lt; 0.01), compared with control group there was a significant difference (P lt; 0.01); 3. treatment group, BMI was significantly reduced compared with before treatment there was a significant difference (P lt; 0.01), compared with control group there was a significant difference (P lt; 0.01); 4. patients treated with FPG, 2hPG, HbA1C were significantly lower compared with before treatment there was a significant difference (P lt; 0.01), compared with the control group, there was a significant difference (P lt; 0.05); 5. patients treated with FINS, IRI were significantly lower compared with before treatment there was a significant difference (P lt; 0.01), and control group there was significant difference (P lt; 0.05); IAI significantly increased, compared with before treatment there was a significant difference (P lt; 0.01), compared with control group there was a significant difference (P lt; 0.01) ; 6 patients treated with TC, TG, LDL-C were significantly lower compared with before treatment there was a significant difference (P lt; 0.01), compared with the control group, there was a significant difference (P lt; 0.05); HDL -C was significantly increased, compared with before treatment there was significant difference (P lt; 0.05), compared with the control group, there was a significant difference (P lt; 0.01); 7. patients treated with various indicators Hemorheologic significantly reduced, compared with before treatment there was a significant difference (P lt; 0.01), compared with control group there was a significant difference (P lt; 0.01); 8. treatment group, the total effective rate was 83.3% in the control group, the total efficiency 66.7%, total effective rate in both groups there was a significant difference (P lt; 0.05). Conclusion: This study enriches the TCM to improve insulin resistance in type 2 diabetes theoretical content, verify Shengmai hypoglycemic drink \

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