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Research and Development of Healthy Food with Tiantai Lindera Root

Author: HeGuoQing
Tutor: JinJian；WangLi
School: Jiangnan University
Course: Industry Technology and Engineering
Keywords: Rooftop aggregata Security Spray granulation Anti-fatigue Health care products
CLC: R151
Type: Master's thesis
Year: 2009
Downloads: 189
Quote: 0
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Abstract


Ancient literature rooftop the aggregata non-toxic, and Zhejiang Tiantai local civil with a wide range of therapeutic foundation. Thesis rooftop aggregata as the main raw material for the research and production of fine particle health food in Taiwan Ukraine. The use of modern toxicological tests and assessment to determine and verify the rooftop aggregata raw materials and finished Taiwan Ukraine toxicity and the role of the fine particles, which laid the foundation for the future development of raw materials, roofs aggregata. The main conclusions are as follows: paper made rooftop aggregata big mouse oral acute toxicity of the maximum tolerated dose (MTD) test, male and female gender are than 20.0g/kg weight, is a non-toxic class, no mutagenicity substances; Ames test, mouse bone marrow micronucleus test and mouse sperm abnormality test were negative, indicating the rooftop aggregata no mutagenicity. 90d feeding study in rats found no animal poisoning symptoms, gross anatomy and histology observed no abnormal pathological changes had no significant effect on rat body weight, food intake, food utilization, blood, blood biochemistry, further evidence of the rooftop of the Ukrainian drug raw material is safe. Aggregata doses> 1.1 g / kg, can significantly improve the swimming time of mice bearing heavy burdens, reducing the area of ??mice swim blood lactate (P <0.05), that aggregata relieve physical fatigue. Chosen as the main raw material of the rooftop aggregata Describe Desk Ukrainian fine particles recipe. Taiwan Ukrainian the fine particle alcohol precipitation best conditions: extract relative density 1.20g/mL (60 ℃ determination), 47.5% alcohol precipitation 48h, and impurity removal efficiency of 22.5%, polysaccharides and saponins were determined by orthogonal test 3.93 g and 3.89g, comprehensive rating of 95.0. Spray pressure, spray flow, inlet air temperature spray drying granulation effect is significant. 1000 per package add accessories 2.6kg (sugar alcohols 0.8kg, the dextrin 1.8kg); spray outside pressure of 2.2MPa, the internal pressure of 1.8MPa, spray flow 0.20L/min, inlet air temperature 55 ° C, the yield reached 93.9 %. The pilot product quality and stability of ,37-40 ℃, relative humidity of 70% -80% of the next 3 months storage, saponins and polysaccharides content of active ingredients and basic health indicators remain unchanged. Large, the maximum tolerated dose of oral acute toxicity in mice is greater than the the 20g/kg weight; Taiwan Ukraine fine particles can be safe to eat by the Ames test, mouse bone marrow micronucleus test and mouse sperm abnormality test. Taiwan Ukraine fine particles 30d feeding study in rats found that rats weight, total food utilization and weekly food utilization, blood biochemistry, organ weight and dirty body ratio and histopathological examinations were no significant differences between the control group. Taiwan Ukraine fine particles to mice orally administered 30d, can significantly extend the swimming time of mice to improve mouse movement glycogen content, lower serum urea content in mice after exercise and swimming after 10min blood lactate content, once again proved Desk Ukrainian fine particles have a role in alleviating physical fatigue.

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CLC: > Medicine, health > Preventive Medicine,Health > Nutrition, hygiene,food hygiene > Nutrition
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