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Objective To observe the soup flavored Xijiaodihuang signs and symptoms of chronic hepatitis, liver function and liver fiber three, HBV-DNA, the impact of imaging to verify soup flavored Xijiaodihuang therapeutic effect, providing for the treatment of chronic hepatitis B clinical basis, better guide clinical application. Methods A randomized controlled trial method, in accordance with Annex I, II standard 120 patients with chronic hepatitis B were randomly divided into a treatment group of 60 patients and a control group of 60 patients. Both groups were given oral conventional water LIN Jia 70mg / time, 3 times / d, compound amino acid capsules 6mg / time, 2 times / d, the treatment group in the conventional treatment therapy based on the use of high-dose Xijiaodihuang decoction (buffalo horn , habitat, Dan, Phyllanthus, dandelion, honeysuckle, violet, herb) decoction, day 1, orally 2 times the control group were treated with placebo. Treatment for 6 months were observed signs and symptoms, liver function, liver fibrosis three, HBV-DNA and radiographic changes, using SPSS10.0 statistical analysis software, measurement data using t test, count data using X2 test, to evaluate its efficacy. Results ① improvement of clinical symptoms and signs Huang Tang Jiawei rhino horn can significantly improve the clinical symptoms and signs: two weeks in the treatment of the two groups did not differ significantly (p gt; 0.05); 4 weeks after treatment, the treatment group, 43 cases symptoms (75% ), while the control group was 30 cases (54%), the two groups, the difference was statistically significant (p lt; 0.05); ② liver function normalization condition can effectively reduce ALT, AST, GGT, TB levels, compared with the control group (P lt; 0.05); ③ liver fibrosis index changes can significantly reduce the HA, LN, CIV level, compared with the control group were significantly different (P lt; 0.05); ④ HBV-DNA and efficient treatment and control groups before and after treatment no HBV-DNA negative conversion, but the treatment group decreased 2logcopy HBV-DNA quantitation values ??compared with control group, the treatment group was 27.5% in the control group was 3.5%, compared to the two groups was statistically significant (p lt; 0.05); ⑤ imaging changes before and after treatment doors, splenic vein diameter and spleen, there was no significant change in the thickness difference (P gt; 0.05), compared with no difference in the two groups (P gt; 0.05), prompted the two groups on narrow doors, splenic vein diameter and thickness of spleen had no significant effect. Conclusion Jiawei Xijiaodihuang decoction can significantly improve the signs and symptoms of chronic hepatitis, liver function and liver fibrosis, to some extent inhibited HBV-DNA, and no significant adverse reactions, liver JiangMei is an effective anti- fibrosis, anti-viral medicine.
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