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Objective: To observe the impact of radio frequency ablation (RFA) of elderly patients with primary hepatocellular carcinoma (PHC) in patients with liver biochemistry, and related complications, evaluate its security. Methods: 54 cases of elderly PHC patients, aged 60-79 years (median age 67 years). All patients by biopsy taken a clear diagnosis of pathological liver lesions smaller than 3, the maximum diameter of ≤ 6cm. 54 cases of liver function in patients with Child-Pugh classification 45 cases: A grade, B grade nine cases. 13 patients with hypertension, 10 patients with diabetes mellitus. Record preoperative and postoperative alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin (TBIL), albumin (ALB), such as liver biochemistry: record preoperative and postoperative alpha-fetoprotein (AFP) value ; records the occurrence of complications, RFA treatment in order to evaluate the security of the elderly PHC patients affected by Pugh. Results: RF preoperative, postoperative 1 week and 2 weeks after surgery liver biochemistry check. 1 week after surgery in patients with ALT.AST than before surgery was significantly higher, the difference was statistically significant (p lt; 0.01), but after two weeks basically reduced to preoperative levels; ALB detection values ??after 1 week decreased compared with the preoperative difference was statistically significant (p lt; 0.01), two weeks after surgery than after 1 week continue to reduce, the difference was statistically significant (p lt; 0.01) In addition, we found that RFA the TBIL detection value no significant impact, preoperative and postoperative 1 week, 2 weeks after the the TBIL detection value was no significant difference (p gt; 0.05). Fever, 17 cases (31.48%), abdominal pain in 20 cases (37.04%), nausea and vomiting in 3 cases (5.56%), pleural effusion in 2 cases (3.7%), pulmonary embolism (1.85%), electrode skin burns patients ( 1.85%). Grading with liver function decline, increased incidence of fever, abdominal pain and other complications, and the difference was statistically significant (p lt; 0.05). Detected in 54 patients in the preoperative the AFP value positive in 15 cases (27.78%), after 1 week for review, the results showed that 80% of patients with AFP values ??decreased to varying degrees compared with the preoperative, 53.33% of the patient's blood AFP value declined by more than 50%, 20% of patients with AFP value was increased further elevated postoperative AFP by CT or MRI, found that the lesion persists strengthen Conclusion: 1 RFA treatment of patients with liver to some extent damage after 1 week showed RF patients with significantly increased ALT, AST than preoperative levels, but recovered to about two weeks. 2 RFA treatment of elderly patients with primary liver cancer severe complication rate is low, the majority of complications were transient injury. 3 graded with liver function decline, increased incidence of fever, abdominal pain and other complications, therefore should actively improve the preoperative liver function. 4 RFA in elderly patients with primary liver cancer safe, effective treatment methods.
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